Neuropsychologic Impairment in Children With Rolandic Epilepsy

Frontal Lobe Epilepsies: Neuropsychological and Behavioral Consequences in Children

“…So this study demonstrated that BECTS influences a language network that involves the more anterior, and therefore frontal cerebral regions (Lillywhite et al, 2009). Difficulties have also been reported in academic perfomances (Nicolai et al, 2007) and learning, with deficits in reading (Ay et al, 2009;Fonseca et al, 2009;Papavasiliou et al, 2005;Piccirilli et al, 2008;Staden et al, 1998) and spelling (Monjauze et al, 2005;Papavasiliou et al, 2005;Staden et al, 1998). Memory also seems to be negatively influenced by spikes in the centrotemporal area: there are reports of difficulties in short-term verbal memory (Danielsson & Petermann, 2009;Northcott et al, 2005;Weglage et al, 1997), visuo-spatial memory (Baglietto et al 2001; www.intechopen.com Danielsson & Petermann, 2009;Volkl-Kernstock et al, 2009) and long-term verbal memory (Northcott et al, 2005) as well as in the learning of verbal information (Croona et al, 1999;Staden et al, 1998).…”

“…Danielsson & Petermann (2009) found verbal and non-verbal difficulties relating to articulation, auditory and visual memory, language comprehension and visual-constructive performance, also in 25 BECTS children aged 4 -7 years when compared with 25 healthy controls. Finally, studies on executive functions in children with BECTS identified mild deficits in information processing (Baglietto et al, 2001;D'Alessandro et al, 1990), in inhibitory processes (Deltour et al, 2007(Deltour et al, , 2008, in problem solving (Croona et al, 1999), in cognitive flexibility (Croona et al, 1999;Deltour et al, 2007;Gunduz et al, 1999), and auditory attention (Ay et al, 2009). Recently Cerminara et al (2010) used a computerized test battery to assess attention ability in 21 children with BECTS compared with 21 controls.…”

Language Dysfunction Is Associated with Age of Onset of Benign Epilepsy with Centrotemporal Spikes in Children

“…In addition, atypical EEG characteristics such as electrical status epilepticus during sleep have been associated with cognitive problems in BECTS children [ [9] ] . It has been reported that BECTS children treated with antiepileptic drugs exhibit increased behavioral disorders and learning difficulties compared with those who were not treated, suggesting that antiepileptic treatment may be a risk factor for cognitive dysfunction in BECTS children [10]. The mechanisms underlying antiepileptic drug-induced cognitive dysfunction in BECTS remain unclear.…”

Troubles cognitifs et comportementaux chez l’enfant ayant une épilepsie bénigne à pointes centro-temporales

“…De plus, Metz Lutz et Filippini (2006) notent la persistance de déficits en mémoire à court terme verbale un an après la rémisson, chez des enfants ayant eu des EEG atypiques en phase active. Finalement, Ay et al (2009) observent un maintien des troubles en lecture après la guérison des enfants.…”

“…Toutefois, chez les neuropsychologues, le terme bénin est contesté car ces enfants présentent souvent des atteintes cognitives, qui, selon quelques études, pourraient être maintenues après la rémission (Ay et al 2009 ;Titomanlio, Romano, Romagnuolo & Del Giudice, 2003). Malheureusement, les données de suivis neuropsychologiques de ces enfants ne convergent pas toujours.…”