Neuropsychological Outcome in Children after Frontal Lobe Epilepsy Surgery

Lendt, Michael; Gleißner, Ulrike; Helmstaedter, C.; Sassen, Robert; Clusmann, Hans; Elger, Christian E.

doi:10.1006/ebeh.2001.0296

Cited by 89 publications

(51 citation statements)

References 22 publications

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“…Stable or small changes in IQ after epilepsy surgery have been reported in short-term and long-term follow-up studies [18,[26][27][28][29][30]. Cognitive stability between two and ten years was reported after temporal lobe surgery in adults [31].…”

Section: Discussionmentioning

confidence: 95%

Cognitive development from two to ten years after pediatric epilepsy surgery

Viggedal

Kristjánsdóttir

Olssøn

et al. 2012

Epilepsy & Behavior

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Section: Discussionmentioning

confidence: 95%

Cognitive development from two to ten years after pediatric epilepsy surgery

Viggedal

Kristjánsdóttir

Olssøn

et al. 2012

Epilepsy & Behavior

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“…However, many patients with a low IQ benefitted from surgery, especially patients with lesions [38,39]. The neuropsychological performance of children with frontal lobe epilepsy before and 1 year after surgery was found to have a favorable cognitive outcome [40]. Similarly, another study, with a long follow-up of up to 6 years, showed that surgery did not adversely affect the cognitive and neuropsychological outcome after surgery [41,42].…”

Section: Discussionmentioning

confidence: 99%

Epilepsy Surgery in a Pediatric Population: A Retrospective Study of 129 Children from a Tertiary Care Hospital in a Developing Country along with Assessment of Quality of Life

Dagar¹,

Chandra²,

Chaudhary³

et al. 2011

Pediatr Neurosurg

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Purpose: To assess the outcome of a pediatric population operated for drug-resistant epilepsy from a large tertiary care center in India. Methods: Retrospectively: quality of life (QOL); prospectively: preoperative assessment included interictal EEG, MRI (as per epilepsy protocol), video-EEG. Ictal SPECT (with subtraction) and PET were performed when required. QOL scores were assessed using the HASS or SSQ for seizure severity, Quality of Life in Childhood Epilepsy (QOLCE) for QOL, and Child Behavior Check List (CBCL) for behavior. Results: 142 were operated from January 2000 to June 2011 by the senior author. 118 patients with at least 1 year of follow-up were included in the study. Mean age at surgery was 9.8 ± 4.3 years. In addition, 40 patients underwent QOL assessment prospectively both before and after surgery. Mean duration of epilepsy was 5.3 ± 3.3 years. A class I outcome (Engel’s) was seen in 79.5% patients, class II in 8.6%, class III in 10.7%, and class IV in 1 patient. As per surgical procedures, class I outcome in patients who underwent temporal resection, hemispherotomy and extratemporal resection was 76, 87 and 72%, respectively. QOL scores correlated with duration of seizures, epileptic encephalopathy and outcome of surgery, but not with side of surgery, age and sex. Conclusions: This study, the largest reported from India, has demonstrated satisfactory results for epilepsy surgery in children.

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“…Lendt and colleagues investigated the neuropsychological function of children with FLE before and 1 year after surgery (Lendt et al 2002), and compared their performance to children who underwent temporal lobe surgery for seizures. The FLE group demonstrated higher intellectual functioning prior to surgery but were more impaired in manual motor coordination than the TLE group.…”

Section: Frontal Lobe Epilepsymentioning

confidence: 99%

Neuropsychological Deficits in Childhood Epilepsy Syndromes

MacAllister

Schaffer

2007

Neuropsychol Rev

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Seizure disorders are relatively common in childhood, and the International League Against Epilepsy (ILAE) provides a hierarchical classification system to define seizure types. At the final level of classification, specific epilepsy syndromes are defined that represent a complex of signs and symptoms unique to an epilepsy condition. The present review discusses the issues related to several of these epilepsy syndromes in childhood, including those classified as generalized idiopathic epilepsies (e.g., childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy), focal epilepsies (benign rolandic epilepsy, occipital epilepsy, temporal lobe epilepsy, frontal lobe epilepsy) and the "epileptic encephalopathies," including Dravet's Syndrome, West Syndrome, Lennox-Gastaut Syndrome, Myoclonic Astatic Epilepsy, and Landau-Kleffner Syndrome. For each syndrome, the epidemiology, clinical manifestations, treatments, and neuropsychological findings are discussed.

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Neuropsychological Outcome in Children after Frontal Lobe Epilepsy Surgery

Cited by 89 publications

References 22 publications

Cognitive development from two to ten years after pediatric epilepsy surgery

Cognitive development from two to ten years after pediatric epilepsy surgery

Epilepsy Surgery in a Pediatric Population: A Retrospective Study of 129 Children from a Tertiary Care Hospital in a Developing Country along with Assessment of Quality of Life

Neuropsychological Deficits in Childhood Epilepsy Syndromes

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