Neurosurgery for intracranial meningioma in patients aged more than 80 years: benefits and rationale

Joubert, Christophe; Sellier, Aurore; Sahuc, P.; Beucler, Nathan; Desse, Nicolas; Corvilain, Bernard; Cungi, Pierre-Julien; Dagain, Arnaud

doi:10.1080/02688697.2021.1875397

Cited by 3 publications

(1 citation statement)

References 27 publications

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“…These differences in outcomes highlight the need for an internationally agreed convention for defining and grading complications after meningioma surgery to enable benchmarking and valuable comparisons among different cohorts. The proposed scoring system by Clavien and Dindo is one such possibility [7,16].…”

Section: Perioperative Morbiditymentioning

confidence: 99%

Older meningioma patients: a retrospective population-based study of risk factors for morbidity and mortality after neurosurgery

2022

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Background Meningioma is the most common primary CNS tumour. Most meningiomas are benign, and most patients are 65 years or older. Surgery is usually the primary treatment option. Most prior studies on early surgical outcomes in older patients with meningioma are small, and there is a lack of larger population-based studies to guide clinical decision-making. We aimed to explore the risks for perioperative mortality and morbidity in older patients with meningioma and to investigate changes in surgical incidence over time. Methods In this retrospective population-based study on patients in Sweden, 65 years or older with surgery 1999–2017 for meningioma, we used data from the Swedish Brain Tumour Registry. We analysed factors contributing to perioperative mortality and morbidity and used official demographic data to calculate yearly incidence of surgical procedures for meningioma. Results The final study cohort included 1676 patients with a 3.1% perioperative mortality and a 37.6% perioperative morbidity. In multivariate analysis, higher age showed a statistically significant association with higher perioperative mortality, whereas larger tumour size and having preoperative symptoms were associated with higher perioperative morbidity. A numerical increased rate of surgical interventions after 2012 was observed, without evidence of worsening short-term surgical outcomes. Conclusions Higher mortality with increased age and higher morbidity risk in larger and/or symptomatic tumours imply a possible benefit from considering surgery in selected older patients with a growing meningioma before the development of tumour-related symptoms. This study further underlines the need for a standardized method of reporting and classifying complications from neurosurgery.

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Section: Perioperative Morbiditymentioning

confidence: 99%