Neurosyphilis unter dem Bild einer „Migräne mit Aura”

Sartor, Heino; Thoden, U.

doi:10.1007/s004820050183

Cited by 5 publications

(3 citation statements)

References 2 publications

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“…In addition, the occurrence of neurosyphilis with the unique clinical manifestation of migraine is very rare. In the literature, there is only one corresponding case [10]. In conclusion, the possibility of neurosyphilis should be taken into account in the differential diagnosis of a persistent headache which does not respond to medication (even if it could easily be attributed to migraine), as the condition is fairly common in developing countries.…”

Section: Discussionmentioning

confidence: 99%

An unusual presentation of neurosyphilis as a probable migraine

et al. 2010

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Section: Discussionmentioning

confidence: 99%

An unusual presentation of neurosyphilis as a probable migraine

et al. 2010

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“…Of the 53 "nonstructural" cases, 13 fulfilled ICHD criteria for MWA (Figure 2). 65,66,68,72,77,82,83,86,87,92,98 In these cases, aura was assumed to be caused by cardiac myxoma (n = 1), viral meningitis (n = 1), head trauma (n = 1, severity not reported), idiopathic intracranial hypertension (n = 1), neurosyphilis (n = 1), cerebral venous thrombosis (n = 1), stellate ganglion block (n = 1), cardiac ablation (n = 4), and the presence of prosthetic heart valves (n = 2). Aura was associated with headache in all cases and preceded the headache in nine.…”

Section: Cases-nonstructuralmentioning

confidence: 99%

Symptomatic migraine: A systematic review to establish a clinically important diagnostic entity

et al. 2021

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Objective To determine if a clinical presentation indistinguishable from migraine can occur due to an underlying condition or pathology, that is, "symptomatic migraine." Background It is currently not clear whether migraine truly can be caused by an underlying condition or pathology. Characterization of the etiology and clinical features of possible symptomatic migraine is of significant clinical importance and further may help elucidate the pathophysiology of migraine. Methods We devised operational diagnostic criteria for “symptomatic migraine” and “possible symptomatic migraine” requiring strong evidence for a causal relation between underlying cause and migraine symptoms adhering strictly to diagnostic criteria. PubMed was searched for case reports of symptomatic migraine from inception to March 2020. Only articles published in English or German were included. No restrictions were placed on study design. Relevant references in the articles were also included. Papers were systematically reviewed by two independent reviewers for detailed clinical features of migraine as well as the proposed underlying conditions and the effects of treatment of these conditions. Results Our search retrieved 1726 items. After screening, 109 papers comprising 504 cases were reviewed in detail. Eleven patients with migraine with aura (MWA) fulfilled our working criteria for symptomatic migraine, and 39 patients fulfilled our criteria for possible symptomatic migraine. The most common etiologies of symptomatic migraine were arteriovenous malformations, carotid stenosis, dissection or aneurysm, brain infarctions, meningioma, and various intra‐axial tumors. Conclusions Symptomatic MWA, indistinguishable from idiopathic MWA, may occur due to cortical lesions or microembolization. We found no clear evidence supporting the existence of symptomatic migraine without aura although we did identify possible cases. Our findings are limited by the available literature, and we suggest that prospective studies are needed.

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“…das Vorhandensein unspezifischer Symptome (z. B. passagere Sehstörungen, Zephalgien) die klinische Einordnung erschweren [11]. Am häu-figsten sind meningeale und/oder vaskuläre Verlaufsformen [3,5,7].…”

Section: Diskussionunclassified

Neurosyphilis

Otto

Hermans²,

Seifried³

et al. 2005

Nervenarzt

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Diagnosis of herpes simplex encephalitis in the acute stage is based on clinical symptoms (nonspecific prodromi, neuropsychological deficits, epileptic seizures) in combination with typical CSF abnormalities (lymphomonozytic pleocytosis) and MR imaging abnormalities assumed to be typical for herpes simplex encephalitis (increased fluid-attenuated inversion recovery and T2 hyperintensities in the mesiotemporal lobe region). Definite diagnosis of herpes simplex encephalitis is based on positive polymerase chain reaction in the CSF, usually available some days after hospital admission. Suspected herpes simplex encephalitis requires immediate treatment with acyclovir. Bacterial encephalitis caused by spirochetes may present with similar features but requires different treatment. This should therefore be considered in the differential diagnosis of herpes simplex encephalitis. We report a young patient with neurosyphilis whose correct diagnosis could be made only several days after beginning specific treatment.

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Neurosyphilis unter dem Bild einer „Migräne mit Aura”

Cited by 5 publications

References 2 publications

An unusual presentation of neurosyphilis as a probable migraine

An unusual presentation of neurosyphilis as a probable migraine

Symptomatic migraine: A systematic review to establish a clinically important diagnostic entity

Neurosyphilis

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