Neurotensin and Cholesterol Transport*

In order to investigate the source of the additional circulating cholesterol in hypercholesterolemia induced by neurotensin (NT), 12.5 pmol/100 g body weight NT was injected into the tail veins of rats which received by the same route 1 X 10(6) dpm/100 g body weight cholesterol-4-14C 24 hours earlier. Fifteen minutes later the concentration of the labeled plasma cholesterol was the same in the treated animals and in the controls. However, specific activity of plasma cholesterol significantly decreased in rats that received NT, while it remained unchanged in the controls. These data suggest that the additional circulating cholesterol after the intravenous administration of NT was either newly formed or originated in some tissue where equilibrium between endogenous and exogenous cholesterol has not yet been established.

show abstract

Effect of Neurotensin on Specific Activity of Plasma Cholesterol Following Intravenous Administration of Cholesterol-4-¹⁴C

Peric-Golia

Gardner

Peric-Golia

1982

Endocrine Research Communications

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Neurotensin and Cholesterol Transport*

Cited by 1 publication

References 6 publications

Effect of Neurotensin on Specific Activity of Plasma Cholesterol Following Intravenous Administration of Cholesterol-4-¹⁴C

Effect of Neurotensin on Specific Activity of Plasma Cholesterol Following Intravenous Administration of Cholesterol-4-¹⁴C

Contact Info

Product

Resources

About

Neurotensin and Cholesterol Transport*

Cited by 1 publication

References 6 publications

Effect of Neurotensin on Specific Activity of Plasma Cholesterol Following Intravenous Administration of Cholesterol-4-14C

Effect of Neurotensin on Specific Activity of Plasma Cholesterol Following Intravenous Administration of Cholesterol-4-14C

Contact Info

Product

Resources

About

Effect of Neurotensin on Specific Activity of Plasma Cholesterol Following Intravenous Administration of Cholesterol-4-¹⁴C

Effect of Neurotensin on Specific Activity of Plasma Cholesterol Following Intravenous Administration of Cholesterol-4-¹⁴C