Neuroticism and self-esteem as indices of the 
vulnerability to major depression in women

Roberts, Seth B.; Kendler, Kenneth S.

doi:10.1017/s0033291799008739

Cited by 154 publications

(123 citation statements)

References 31 publications

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“…Neuroticism is itself heritable (Jang, Livesley, & Vernon, 1996;Loehlin, McCrae, Costa, & John, 1998), thus possibly accounting for genetic influences on self-esteem level and perceived stability. Past research indicates that self-esteem level shows a genetic correlation with neuroticism (Roberts & Kendler, 1999), although we lack evidence of a similar link with perceived stability. If a shared underlying temperament dimension explained entirely genetic influences on level and perceived stability, we would expect genetic influence on both to be carried by a common genetic factor.…”

contrasting

confidence: 90%

Genetic influences on level and stability of self-esteem

2006

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We attempted to clarify the relation between self-esteem level (high vs. low) and perceived self-esteem stability (within-person variability) by using a behavioral genetics approach. We tested whether the same or independent genetic and environmental influences impact on level and stability. Adolescent twin siblings (n ¼ 183 pairs) completed level and stability scales at two time points. Heritability for both was substantial. The remaining variance in each was attributable to nonshared environmental influences. Shared environmental influences were not significant. Level and stability of self-esteem shared common antecedents via genetic and non-shared environmental influences. Nonetheless, stability was influenced by substantial unique genetic and non-shared environmental influences. The results validate the notion that level and stability are partially autonomous components of self-esteem.

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confidence: 90%

Genetic influences on level and stability of self-esteem

2006

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“…Data on neuroticism reveal consistently that neuroticism is genetically related to both depression (measured categorically or dimensionally) and anxiety. Although to a lesser extent, there is overlap in unique environmental factors between neuroticism, depression and anxiety (Jardine et al 1984 ;Martin et al 1988;Kendler et al 1993 a ;Gustavsson et al 1996 ;Roberts & Kendler, 1999 ;Boomsma et al 2000 ;Fanous et al 2002 ;Ono et al 2002 ;Stein et al 2002). No study found an influence of common environment and thus, no significant correlation between common environmental factors either.…”

Section: Results and Conclusion From Twin And Family Studiesmentioning

confidence: 97%

The co-morbidity of anxiety and depression in the perspective of genetic epidemiology. A review of twin and family studies

et al. 2005

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Background. Co-morbidity within anxiety disorders, and between anxiety disorders and depression, is common. According to the theory of Gray and McNaughton, this co-morbidity is caused by recursive interconnections linking the brain regions involved in fear, anxiety and panic and by heritable personality traits such as neuroticism. In other words, co-morbidity can be explained by one disorder being an epiphenomenon of the other and by a partly shared genetic etiology. The aim of this paper is to evaluate the theory of Gray and McNaughton using the results of genetic epidemiological studies.

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“…This association is partly due to pleiotropic genetic influences (Jardine et al, 1984;Kendler et al, 1993;Mackintosh et al, 2006;Middeldorp et al, 2005;2011;Roberts & Kendler, 1999). Genetic pleiotropy also accounts for the association between neuroticism and borderline personality disorder (Distel et al, 2009).…”

mentioning

confidence: 99%

Genetic and Environmental Stability of Neuroticism From Adolescence to Adulthood

et al. 2015

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Longitudinal studies of neuroticism have shown that, on average, neuroticism scores decrease from adolescence to adulthood. The heritability of neuroticism is estimated between 0.30 and 0.60 and does not seem to vary greatly as a function of age. Shared environmental effects are rarely reported. Less is known about the role of genetic and environmental influences on the rank order stability of neuroticism in the period from adolescence to adulthood. We studied the stability of neuroticism in a cohort sequential (classical) twin design, from adolescence (age 14 years) to young adulthood (age 32 years). A genetic simplex model that was fitted to the longitudinal neuroticism data showed that the genetic stability of neuroticism was relatively high (genetic correlations between adjacent age bins >0.9), and increased from adolescence to adulthood. Environmental stability was appreciably lower (environmental correlations between adjacent age bins were between 0.3 and 0.6). This low stability was largely due to age-specific environmental variance, which was dominated by measurement error. This attenuated the age-to-age environmental correlations. We constructed an environmental covariance matrix corrected for this error, under the strong assumption that all age-specific environmental variance is error variance. The environmental (co)variance matrix corrected for attenuation revealed highly stable environmental influences on neuroticism (correlations between adjacent age bins were between 0.7 and 0.9). Our results indicate that both genetic and environmental influences have enduring effects on individual differences in neuroticism.

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Neuroticism and self-esteem as indices of the vulnerability to major depression in women

Cited by 154 publications

References 31 publications

Genetic influences on level and stability of self-esteem

Genetic influences on level and stability of self-esteem

The co-morbidity of anxiety and depression in the perspective of genetic epidemiology. A review of twin and family studies

Genetic and Environmental Stability of Neuroticism From Adolescence to Adulthood

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