Neurotoxic Effects of Clinoquinol, Mouse

Koga, Makoto; Tateishi, Jun; Sato, Yuji; Matsuki, Kei

doi:10.1007/978-3-642-83516-2_5

Cited by 2 publications

(4 citation statements)

References 13 publications

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“…Neuronal cell loss has been induced in rats by carotid artery ligation (Bendel et al 2005) and by treatment with trimethyltin (Little et al 2002;Philbert, Billingsley, and Reuhl 2000) or neurotoxic analogs of excitatory amino acids that activate ionotropic glutamate receptors, such as kainic acid (Liang et al 2007). Clinoquinol, a well-known cause of subacute myelooptic neuropathy in humans, induces moderate loss of neurons in the hippocampus of mice (Koga et al 1988).…”

Section: Neuron-cell Bodymentioning

confidence: 99%

“…The hamartomatous character of meningioangiomatosis is evident by its frequent occurrence in human patients with neurofibromatosis type 2 (Stemmer-Rachamimov et al 1997). Meningiomas arising in the background of meningioangiomatosis in humans have a benign clinical course, although they pathologically and radiologically mimic invasive meningiomas (Kim et al 2002).…”

Section: Generalmentioning

confidence: 99%

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Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems

et al. 2012

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Harmonization of diagnostic nomenclature used in the pathology analysis of tissues from rodent toxicity studies will enhance the comparability and consistency of data sets from different laboratories worldwide. The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of four major societies of toxicologic pathology to develop a globally recognized nomenclature for proliferative and nonproliferative lesions in rodents. This article recommends standardized terms for classifying changes observed in tissues of the mouse and rat central (CNS) and peripheral (PNS) nervous systems. Sources of material include academic, government, and industrial histopathology databases from around the world. Covered lesions include frequent, spontaneous, and aging-related changes as well as principal toxicant-induced findings. Common artifacts that might be confused with genuine lesions are also illustrated. The neural nomenclature presented in this document is also available electronically on the Internet at the goRENI website (http://www.goreni.org/).

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Section: Neuron-cell Bodymentioning

confidence: 99%

Section: Generalmentioning

confidence: 99%

Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems

et al. 2012

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“…82 Clioquinol, a well-known cause of subacute myelooptic neuropathy in humans, induces convulsions causing moderately decreased neuronal cellularity in the hippocampus of mice. 83 In rats, spontaneous, age-related decreases in neuronal cellularity affect Purkinje cells, 84 neurons in the suprachiasmatic nucleus, 85 and subcortical neurons. 86 Other reports describe spontaneous decreases in neuronal cellularity in the hippocampal CA 3 region of rats in association with deficits in working memory.…”

Section: Commentmentioning

confidence: 99%

“…82 Clioquinol, a well-known cause of subacute myelo-optic neuropathy in humans, induces convulsions causing moderately decreased neuronal cellularity in the hippocampus of mice. 83…”

Section: Nomenclaturementioning

confidence: 99%

Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems: New and Revised INHAND Terms

et al. 2020

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Harmonization of diagnostic terminology used during the histopathologic analysis of rodent tissue sections from nonclinical toxicity studies will improve the consistency of data sets produced by laboratories located around the world. The INHAND Project ( International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a cooperative enterprise of 4 major societies of toxicologic pathology to develop a globally accepted standard vocabulary for proliferative and nonproliferative lesions in rodents. A prior manuscript ( Toxicol Pathol 2012;40[4 Suppl]:87S-157S) defined multiple diagnostic terms for toxicant-induced lesions, common spontaneous and age-related changes, and principal confounding artifacts in the rat and mouse central nervous system (CNS) and peripheral nervous system (PNS). The current article defines 9 new diagnostic terms and updates 2 previous terms for findings in the rodent CNS and PNS, the need for which has become evident in the years since the publication of the initial INHAND nomenclature for findings in rodent neural tissues. The nomenclature presented in this document is also available electronically on the Internet at the goRENI website ( http://www.goreni.org/ ).

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Neurotoxic Effects of Clinoquinol, Mouse

Cited by 2 publications

References 13 publications

Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems

Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems

Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems: New and Revised INHAND Terms

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