Neurotoxicological assessment of pendimethalin in freshwater fish Channa punctata Bloch

In Vivo Acute and Chronic Toxicity of Pendimethalin on Haematological and Biochemical Indices of African Catfish, Clarias gariepinus (Burchell 1822)

“…Furthermore, the inhibition of SOD in each tissue may explain the increased MDA levels in the tissues as a result of peroxidative damage. The elevated MDA levels observed in this study are consistent with previous observations made on fish exposed to pendimethalin (El-Sayed et al, 2013;Tabassum et al, 2015) and other herbicides (Guilherme et al, 2012;Nwani et al, 2014;Owolabi and Omotosho, 2017). The significant reduction in AChE activity is consistent with the observation of Tabassum et al (2007) and further corroborates the suggestion of Matos et al (2007) that reduced AChE activity is related to high MDA levels.…”

“…California Department of Pesticide Regulation (CDPR, 2008) reported that the use of pendimethalin increased by 29% in 2008, with more than 1.4 million pounds on agricultural commodities, including landscape maintenance and rights of way. Only a few authors have reported the toxicity of pendimethalin on haematological and biochemical indices of fish species such as Oreochromis niloticus (El-Sharkawy et al, 2011;El-Sayed et al, 2013), Oncorhynchus mykiss (Danion et al, 2014); Channa punctata (Tabassum et al, 2015;Tabassum et al, 2016). In tropical Africa, other than the reports of Abd-Algadir et al 2011 Moustafa et al (2016) on the effects of pendimethalin in fish, no investigation has been conducted to determine the effects of pendimethalin on African tropical freshwater fishes, despite the constant use of the herbicide.…”

Potential effects of low molecular weight phthalate esters (C16H22O4and C12H14O4) on the freshwater fish Cyprinus carpio

“…118 The decline in brain ATPase activity in the fish Channa punctata may be due to LPO induced structural and functional alteration of the brain plasma membrane. 119 Cholinesterase activity A significant ( p < 0.05) decrease in brain ChE activity was noted at all concentrations in both toxicant exposed groups (Fig. 9).…”

Continuous Agrochemical Treatments in Agroecosystems Can Modify the Effects of Pendimethalin-Based Herbicide Exposure on Immunocompetence of a Beneficial Ground Beetle

“…Thus far, there have been few data on the toxicity of dinitroaniline and, especially, pendimethalin. Earlier studies have reported on the latter's genotoxicity and cytotoxicity effects, as related to its capability to bind DNA [72], in the non-target freshwater fish Channa punctatus [14,15]. Moreover, an increase of the incidence in chromosomal aberration and micronuclei has been recorded at the cellular level in Chinese hamster ovaries [73], lung fibroblast cells [74], and mouse bone marrow [75].…”

“…Because of its low affinity for animal tubulins, the effects of pendimethalin have mainly been investigated in soil microbiota [12]. Very few studies have addressed potential toxicity following the application of sublethal doses of pendimethalin on a low number of aquatic organisms [11,14,15], as well as on non-target soil invertebrates, including insects [16,17]. This raises the question of whether exposure to pendimethalin may be harmful and can cause potential direct (feeding on contaminated prey or absorption by contact) and indirect (depletion of food) effects on non-target species.…”