Neurotoxins and Autism

Abstract

Recently, a great concern has risen about the increasing prevalence of autism as a neurodevelopmental disorder. Environmental factors as significant contributors to children's health through a wide range of routes are linked to remarkable increases in this disorder. It is well known and accepted that young children are more vulnerable to environmental toxins, compared to adults. Modern day lifestyles with more mercury and lead exposures, fast food, cell phones, and microwaves place children at higher risk of neurotoxicity. Moreover, a huge number of synthetic chemicals termed as high-productionvolume (HPV) chemicals are found in many products such as medications, cosmetics, building materials, plastic, and car fuels. These HPVs highly contribute to brain damage in developing infants. Other environmental toxins include thalidomide, valproic acid, misoprostol, and many infectious agents among which are pathogenic bacteria or their metabolites are found to be neurotoxic and/or linked to incidences of autism. This chapter summarizes the most important routes of exposure to environmental neurotoxins and explains how these toxins are related to the remarkable increase in the prevalence of autism through different etiological mechanisms such as oxidative stress, neuroinflammation, impaired neurochemistry and glutamate excitotoxicity.

Determination of Optimum Treatment for Seeds Content from Vitamin B6 of Vicia faba L. Plant growing under water stress

“…It gives metabolic products to release energy and contributes to the conversion of linoleic acid to acronic acid, It was also found that vitamin B6 may prevent elevated homocysteine levels in the blood, which is associated with an increased risk of cardiovascular disease, which also accelerates arterial disease [6] . Glycerrhiza is one of the legume family plants, Glycyrrhizin glubara is considered to be the most important and best species because it is rich in the active substance with a sweet taste called glycyrrhizin [7], [8] , in addition to glucose,it is 40 times as sweet as sugar cane [9]. Glycerrhiza is rich in many chemical compounds such as, glycyrrhizin, flavonoids, etc.…”