2016
DOI: 10.5213/inj.1620edi010
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Neurourological Application of Neurogenesis and Inflammation and Pain Mechanisms of Rocuronium Bromide

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“…The abnormal expressions of various pain mediators in vivo will lead to acute pain, and the detection of the level of patient mediators can objectively reflect the subjective pain degree of patients. The effect threshold or stimulation range of the combination of multiple drugs on pain mediators is wider than that of drugs alone, and the effect on nervous system is better than that of drugs alone (19,20). Some studies have shown that sufentanil combined with butorphenol has a stronger analgesic effect than butorphenol alone (21), the combination of dexmedetomidine and sufentanil in the treatment of PCIA after thoracoscopic lobectomy has better analgesic effect and more stable blood flow dynamics than that of sufentanil alone, and can reduce the dose of sufentanil and the adverse reaction (22).…”
Section: Discussionmentioning
confidence: 99%
“…The abnormal expressions of various pain mediators in vivo will lead to acute pain, and the detection of the level of patient mediators can objectively reflect the subjective pain degree of patients. The effect threshold or stimulation range of the combination of multiple drugs on pain mediators is wider than that of drugs alone, and the effect on nervous system is better than that of drugs alone (19,20). Some studies have shown that sufentanil combined with butorphenol has a stronger analgesic effect than butorphenol alone (21), the combination of dexmedetomidine and sufentanil in the treatment of PCIA after thoracoscopic lobectomy has better analgesic effect and more stable blood flow dynamics than that of sufentanil alone, and can reduce the dose of sufentanil and the adverse reaction (22).…”
Section: Discussionmentioning
confidence: 99%