Neutron activation analysis of trace elements in skin. IX. Rubidium in normal skin

Portnoy, Benjamin; Dyer, A.; Molokhia, Anat

doi:10.1111/j.1365-2133.1981.tb00776.x

Cited by 3 publications

(1 citation statement)

References 17 publications

(8 reference statements)

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“…In human skin, the concentration of zinc is higher in the epidermis (50-70 µg/g dry weight) compared to the dermis (10-15 µg/g dry weight). This difference may reflect the involvement of zinc-dependent RNA and DNA polymerases in the mitotically active basal cells [299][300][301][302]. Immunohistochemical and in situ hybridization localization studies have revealed that in normal skin, high levels of metallothionein (MTs) are found in the basal epidermis, while their concentrations are reduced in postmitotic keratinocytes, reticuloendothelial cells, and fibroblasts [303][304][305].…”

Section: Zinc (Zn)mentioning

confidence: 99%

An Overview of Scaffolds and Biomaterials for Skin Expansion and Soft Tissue Regeneration: Insights on Zinc and Magnesium as New Potential Key Elements

Hassan,

Krieg,

Zinser

et al. 2023

Polymers

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The utilization of materials in medical implants, serving as substitutes for non-functional biological structures, supporting damaged tissues, or reinforcing active organs, holds significant importance in modern healthcare, positively impacting the quality of life for millions of individuals worldwide. However, certain implants may only be required temporarily to aid in the healing process of diseased or injured tissues and tissue expansion. Biodegradable metals, including zinc (Zn), magnesium (Mg), iron, and others, present a new paradigm in the realm of implant materials. Ongoing research focuses on developing optimized materials that meet medical standards, encompassing controllable corrosion rates, sustained mechanical stability, and favorable biocompatibility. Achieving these objectives involves refining alloy compositions and tailoring processing techniques to carefully control microstructures and mechanical properties. Among the materials under investigation, Mg- and Zn-based biodegradable materials and their alloys demonstrate the ability to provide necessary support during tissue regeneration while gradually degrading over time. Furthermore, as essential elements in the human body, Mg and Zn offer additional benefits, including promoting wound healing, facilitating cell growth, and participating in gene generation while interacting with various vital biological functions. This review provides an overview of the physiological function and significance for human health of Mg and Zn and their usage as implants in tissue regeneration using tissue scaffolds. The scaffold qualities, such as biodegradation, mechanical characteristics, and biocompatibility, are also discussed.

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Section: Zinc (Zn)mentioning

confidence: 99%

An Overview of Scaffolds and Biomaterials for Skin Expansion and Soft Tissue Regeneration: Insights on Zinc and Magnesium as New Potential Key Elements

Hassan,

Krieg,

Zinser

et al. 2023

Polymers

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Rubidium in psychiatry: Research implications

Malek-Ahmadi

Williams

1984

Pharmacology Biochemistry and Behavior

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The distribution of intracellular alkali metals in Reference Man

Williams¹,

Leggett²

1987

Phys. Med. Biol.

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A review of recent literature and a re-analysis of data used in Publication 23 of the International Commission on Radiological Protection (ICRP) have revealed several problems regarding the distribution of the predominantly intracellular alkali metals potassium, rubidium and caesium in ICRP Reference Man. In this paper we re-evaluate the distribution of the intracellular alkali metals in humans and we offer an approach for selecting reference concentrations for the organs of a typical adult human. For non-skeletal tissues, reference values for K, Rb and Cs are determined as a trimmed weighted mean of reported values remaining after studies involving apparently questionable populations or measurement techniques have been eliminated. The skeleton is treated as a special case, with explicit consideration being given to the heterogeneous distribution of these elements among different regions and different types of skeletal tissue. The most significant suggested changes for the intracellular alkali metals are for Rb in the skeleton and total body. ICRP Reference Man has a total Rb content of 0.68 g, compared with our estimate of only 0.25 g, and a skeletal Rb content of 0.21 g, compared with our estimate of only 0.013 g. This has important dosimetric implications for radiorubidium, because the retention model for Rb given in ICRP Publication 30 assigns a large portion of an intake to the skeleton on the basis of the large skeletal Rb content assigned to Reference Man in ICRP Publication 23.

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Neutron activation analysis of trace elements in skin. IX. Rubidium in normal skin

Abstract: SUMMARY Regional variations of levels of rubidium (Rb) in normal adult skin were determined by non‐destructive neutron activation analysis combined with gamma spectroscopy.

Cited by 3 publications

References 17 publications

An Overview of Scaffolds and Biomaterials for Skin Expansion and Soft Tissue Regeneration: Insights on Zinc and Magnesium as New Potential Key Elements

An Overview of Scaffolds and Biomaterials for Skin Expansion and Soft Tissue Regeneration: Insights on Zinc and Magnesium as New Potential Key Elements

Rubidium in psychiatry: Research implications

The distribution of intracellular alkali metals in Reference Man

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