Our understanding of physical phenomena is expressed as modelling. At present, the broadest platform for such modelling is quantum mechanics approach. Unfortunately, many -body systems are usually an extreme challenge for existing methods of quantum mechanics. One has to rely on rather simple, much more straight formed concepts. In this Chapter, such general basic concepts will be shown as ingredients of typical models of nuclear reaction.Several microscopic models have been constructed in order to describe the first stage of proton -nucleus reaction. All of them have the same basis, they describe the reaction as a cascade of nucleon -nucleon collisions, but employing different assumptions. The main difference concerns implemented potential of nucleon -nucleus interaction. One can distinguish the simplest models, which neglect features of the mean field dynamics and employ constant static potential, like a class of Intra -Nuclear Cascade (INC) models. Other, more sophisticated approaches comprise dynamically changing field and minimal fluctuations obtained due to use of test particle method, i.e. models based on Boltzmann -Uehling -Uhlenbeck (BUU) transport equation. There are also models, which include real fluctuations and particles correlations, employing two-and three-body potentials, e.g. Quantum Molecular Dynamics models. The main ideas of the different types of nuclear reaction approaches are described below.In this Chapter, devoted for model-like approach of investigation of nucleon -nucleus reactions, also so-called percolation model is presented. This rather basic model describes fragment mass distributions very well (Section 2.3). 9