Measurements of (γ, p) and (γ, α) photonuclear reaction cross sections are relevant for several nucleosynthesis scenarios, from the primordial Big Bang, to stellar burning, and the p-process. Studies of photonuclear reaction cross sections marked a steady development in the last 20 years with the advent of mono-energetic γ-ray beam facilities and improved detection methods. Charged-particle detection from photon-induced reactions in solid targets is mainly achieved with silicon-strip detectors, while time projection chambers were developed for measurements with active gas targets. This review tracks the evolution of charged-particle detection methods and highlights recent 7 Li(γ, t) 4 He and 16 O(γ, α) 12 C cross section measurements using mono-energetic γ-ray beams.