Neutrophil-to-Lymphocyte Ratio Has a Close Association With Gangrenous Appendicitis in Patients Undergoing Appendectomy

Ishizuka, Mitsuru; Shioiri, Takayuki; Kubota, Keiichi

doi:10.9738/cc161.1

Cited by 144 publications

(150 citation statements)

References 31 publications

Supporting

Mentioning

120

Contrasting

Unclassified

Order By: Relevance

“…The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy are 88.0%, 71.4%, 78.5%, 83.3%, and 80.4% consecutively. 11,13,20 It can be concluded that in this study, the cut-off point for NLR was no better than the other studies because the sensitivity and specificity numbers were still lower. As for the cut-off point for CRP is still superior to the study conducted by Moon H in terms of sensitivity.…”

Section: Exclusion Criteriamentioning

confidence: 62%

Diagnostic value of C-reactive protein and neutrophil-limphocyte ratio in perforated appendicitis at Hasan Sadikin Hospital Bandung

2017

View full text Add to dashboard Cite

Background: The diagnosis of appendicitis depends on the subjective criteria of clinical examination. However, distinguishing acute perforated appendicitis (local peritonitis) and non-perforated is often difficult especially in the elderly population that usually not clinically specific unless it has developed into generalized peritonitis. Between the non-perforated acute appendicitis and perforate should be distinguished because of different surgical approaches. C-reactive protein (CRP) and neutrophil-lymphocyte ratios are known to be associated with various conditions such as malignancy, heart disease, and inflammation, including acute perforated appendicitis. This examination not only is cheaper, but also feasible and available in peripheral hospitals compared to other supports such as ultrasound or CT scan, but this examination has not been routinely used so the purpose of this study is to examine the diagnostic accuracy of both laboratory parameters so as to assist a surgeon to determine whether the case of appendicitis has been perforated or not and can provide information to patients and the families about the diseases and surgical techniques to be performed.Methods: This study used cross sectional analytic in two groups, appendicitis with and without perforation group to know the value of sensitivity, specificity, positive predictor value, negative predictor value, from CRP and RNL in both groups.Results: Of the 46 patients who met the inclusion criteria, the mean age of patients with perforated appendicitis was 33.73±17.101, male sex counted 26 patients (56.5%) and women 20 patients (43.5%). Based on ROC curve analysis, CRP = 76,65 and RNL = 8,825 were obtained, and sensitivity, specificity, positive guess, negative prediction and accuracy value for CRP were 88.0%, 71.4%, 78 %, 5%, 83.3% and 80.4%; While for RNL of 64.0%, 80.9%, 80.0%, NDN, and 71.7%.Conclusions: CRP and RNL have a strong diagnostic value and is moderately strong in cases of perforated appendicitis.

show abstract

Section: Exclusion Criteriamentioning

confidence: 62%

Diagnostic value of C-reactive protein and neutrophil-limphocyte ratio in perforated appendicitis at Hasan Sadikin Hospital Bandung

2017

View full text Add to dashboard Cite

show abstract

“…Ishizuka and colleagues found a significant association between NLR and severity of acute appendicitis. Neutrophil/lymphocyte ratio was significantly different between catarrhal, phlegmonous and gangrenous appendicitis groups [19]. Markar and colleagues were found a higher level of NLR in AA.…”

Section: Discussionmentioning

confidence: 96%

The Change of Neutrophil Lymphocyte Ratio in Acute Appendicitis

Küçük¹

2015

Med-Science

View full text Add to dashboard Cite

show abstract

“…[8] Although several studies have explored the utility of NLR in the diagnosis and prognosis of inflammatory and malignant diseases, very rarely has NLR been used in the diagnosis of AMI. [9][10][11] In the present study, the diagnostic capacity of NLR was evaluated and compared to traditional parameters in such patients.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic utility of the neutrophil-to-lymphocyte ratio in patients with acute mesenteric ischemia: A retrospective cohort study

Tanrıkulu

Sabuncuoğlu

et al. 2015

Ulus Travma Acil Cerrahi Derg

View full text Add to dashboard Cite

BACKGROUND: Acute mesenteric ischemia (AMI) remains fatal in 50-70% of cases. AMI is recognized as a vascular emergency, requiring rapid and efficient clinical evaluation and treatment. In the present retrospective study, the possible utility of the neutrophillymphocyte ratio (NLR) in the early diagnosis of AMI was explored. The potential use of this ratio to distinguish AMI from non-vascular bowel necrosis (NVBN) was investigated.

show abstract

Neutrophil-to-Lymphocyte Ratio Has a Close Association With Gangrenous Appendicitis in Patients Undergoing Appendectomy

Cited by 144 publications

References 31 publications

Diagnostic value of C-reactive protein and neutrophil-limphocyte ratio in perforated appendicitis at Hasan Sadikin Hospital Bandung

Diagnostic value of C-reactive protein and neutrophil-limphocyte ratio in perforated appendicitis at Hasan Sadikin Hospital Bandung

The Change of Neutrophil Lymphocyte Ratio in Acute Appendicitis

Diagnostic utility of the neutrophil-to-lymphocyte ratio in patients with acute mesenteric ischemia: A retrospective cohort study

Contact Info

Product

Resources

About