Neutrophil‐to‐Lymphocyte Ratio May Predict Subclinical Atherosclerosis in Patients with Psoriasis

Balta, İlknur; Balta, Şevket; Demirkol, Sait; Öztürk, Cengiz; Çelik, Turgay

doi:10.1111/echo.12668

Cited by 11 publications

(9 citation statements)

References 9 publications

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“…The NLR is an inexpensive indicator of systemic inflammation, is correlated with the prognosis of various diseases, eg, acute coronary syndrome and acute pancreatitis, and is useful in predicting subclinical atherosclerosis in patients with psoriasis. 21–23 The NLR can be used to predict survival after coronary intervention in non-ST-segment elevation and ST-segment elevation myocardial infarction. 24 , 25 Several reports have suggested the role of inflammation in the regulation of coronary microvascular responses in patients with CSX.…”

Section: Discussionmentioning

confidence: 99%

The Relationship Between the Neutrophil to Lymphocyte Ratio, The Platelet to Lymphocyte Ratio, and Cardiac Syndrome X

Cao¹,

Li²,

Wang³

et al. 2022

RMHP

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Objective This study aims to investigate the relationship between the neutrophil to lymphocyte ratio (NLR), the platelet to lymphocyte ratio (PLR), and cardiac syndrome X (CSX). Methods A total of 102 patients with CSX who were hospitalized in the Cardiology Department of our hospital from December 2018 to December 2020 were enrolled in the CSX group, and 102 subjects who underwent physical examinations during the same period were included in the control group. An automatic blood cell analyzer was adopted to detect the neutrophil count (NC), lymphocyte count (LC), and number of platelets (PLT) in the whole blood of the subjects in both groups, and the NLR and PLR were calculated. Electrocardiography was conducted on the subjects in both groups to detect whether any abnormality existed in the ST segment. The receiver operating curve (ROC) was used to evaluate the diagnostic value of each indicator of CSX, and multivariate logistic regression analysis was adopted for the analysis of the influencing factors. Results No significant differences existed in age, gender, smoking history, or family history of diabetes mellitus, hypertension, and tumors between the two groups ( p > 0.05). When compared with the control group, the NC, PLT, NLR, PLR, and rate of abnormality of the ST segment on the electrocardiogram were significantly higher, and the LC was significantly lower in the CSX group ( p < 0.05). Multivariate logistic regression analysis showed that the ST-segment abnormality (3.95 [2.10~7.41]; NLR > 2.21, 3.46 [1.87~6.39]; and PLR > 119.77, 3.66 [1.99~6.73]) was a correlated risk factor for the occurrence of CSX ( p < 0.05). Conclusion Both the NLR and PLR in patients with CSX were significantly elevated, and both have a certain predictive value for the occurrence of CSX and are expected to be effective biomarkers for CSX.

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Section: Discussionmentioning

confidence: 99%

The Relationship Between the Neutrophil to Lymphocyte Ratio, The Platelet to Lymphocyte Ratio, and Cardiac Syndrome X

Cao¹,

Li²,

Wang³

et al. 2022

RMHP

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“…The parameters, such as MHR, MLR, and NLR, which are easily computed in daily laboratory tests and cost‐effective, are a significant indicator of systemic inflammation in many diseases 30,31 . MHR manifests the efficiency of monocytes that contribute to the development of systemic inflammation and oxidative stress, as well as the effectiveness of HDL‐C, which has anti‐inflammatory and antioxidant effects on the vascular system.…”

Section: Discussionmentioning

confidence: 99%

Can decreased monocyte to HDL ‐cholesterol ratio be a marker indicating the anti‐inflammatory effect of the colchicine in Behçet's disease? A preliminary study

Demirbaş

İslamoğlu

2020

Dermatologic Therapy

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Behçet's disease (BD) is an auto-inflammatory disease characterized by systemic vasculitis. Monocyte to HDL-cholesterol ratio (MHR), monocyte to lymphocyte ratio (MLR), and neutrophil to lymphocyte ratio (NLR) are used as inflammatory markers in many disorders. Colchicine decreases inflammation by suppressing the secretion of pro-inflammatory cytokines. This study aims to examine the effects of colchicine treatment on MHR, MLR, and NLR levels of the patients with BD. In this study, 80 patients, who were with mild/moderate/severe BD based on the Krause's Clinical Severity Scoring for BD and received colchicine treatment for at least 3 months, were evaluated retrospectively. The results of MHR, MLR, NLR, and other hematological parameters were assessed in three groups as follows: precolchicine treatment (Group 1), at the end of the 1st month of the treatment (Group 2), and at the end of the 3rd month of the treatment (Group 3). A total of 80 patients involving 39 (48.75%) females and 41 (51.25%) males, who were treated with colchicine due to the diagnosis of BD, were examined in this study. The mean age of the patients was 36.85 ± 10.659 (18-59) years. The findings showed that there was a statistically significant reduction in MHR, MLR, and NLR levels of postcolchicine treatment

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“…6 The NLR has been widely used to determine the severity of inflammation in inflammatory diseases, malignancies, diabetes mellitus, hypertension, 7 and cardiovascular disease. 8,9 In conclusion, the NLR seems to be a useful inflammatory marker and predictor of the activity of BD. However, more research is required to define its exact role in patient management.…”

mentioning

confidence: 86%

“…6 The NLR has been widely used to determine the severity of inflammation in inflammatory diseases, malignancies, diabetes mellitus, hypertension, 7 and cardiovascular disease. 8,9…”

mentioning

confidence: 99%

The Neutrophil–Lymphocyte Ratio and Behcet Disease

Açıkgöz

2015

Angiology

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Neutrophil‐to‐Lymphocyte Ratio May Predict Subclinical Atherosclerosis in Patients with Psoriasis

Cited by 11 publications

References 9 publications

The Relationship Between the Neutrophil to Lymphocyte Ratio, The Platelet to Lymphocyte Ratio, and Cardiac Syndrome X

The Relationship Between the Neutrophil to Lymphocyte Ratio, The Platelet to Lymphocyte Ratio, and Cardiac Syndrome X

Can decreased monocyte to HDL ‐cholesterol ratio be a marker indicating the anti‐inflammatory effect of the colchicine in Behçet's disease? A preliminary study

The Neutrophil–Lymphocyte Ratio and Behcet Disease

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