Neutrophil to lymphocyte ratio predicts short- and long-term mortality following revascularization therapy for ST elevation myocardial infarction

Sawant, Abhishek C.; Adhikari, Prabhat; Narra, Swapna R.; Srivatsa, Shantanu; Mills, Paul K.; Srivatsa, Sanjay S.

doi:10.5603/cj.a2013.0148

Cited by 100 publications

(86 citation statements)

References 30 publications

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“…(14) NLR has been studied by different investigators in relation to different scoring systems showing CAD severity and it has been shown to be related to NLR by SYNTAX, GRACE and TIMI scores. (15)(16)(17) In our study, similarly, the NLR values were higher in the ACS group than in the control group. Correlation analyzes showed that NLR correlated with high sensitive troponin I, PLR, ST elevation, ST depression, T wave negativity and angina duration.…”

Section: Discussionsupporting

confidence: 58%

Correlations between hematological indicators and other known markers in acute coronary syndromes

Ertürk¹,

Çağlar²,

Bıyık³

2017

ejcm

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Introduction:Recently, many hematologic markers have identified as prognostic and diagnostic indicators in different acute coronary syndrome (ACS) patients. In particular, neutrophil / lymphocyte ratio (NLR) and platelet / lymphocyte ratio (PLR) are recognized as markers in the diagnosis and prognosis of ACS. In this study, our aim was to investigate the correlation between the diagnostic yield of PLR and NLR values and other markers such as troponin in all ACS patients. Material and methods:319 patients admitted to our hospital with ACS and 283 control patients were included in the study. Leukocyte, neutrophil, platelet, lymphocyte counts, PLR, NLR and high sensitive troponin I (HsTnI) measurements were taken.Results: Leukocyte, neutrophil and platelet counts were significantly higher in the ACS group than the controls (p <0.001). Lymphocyte count was significantly lower in the ACS group than the controls (p <0.001). NLR and PLR were found to be significantly higher in the ACS group than the controls (4.0 ± 3.3 vs 2.1 ± 1.4 and 126.3 ± 68.9 vs 106.9 ± 49.4, p <0.001, respectively). NLR was showed significant correlation with HsTnI, PLR, angina time, presence of ST elevation and T wave negativity (p <0.05), and PLR revealed significant correlation with NLR, HsTnI, ST elevation and T wave negativity (p <0.05). Conclusion:Hematologic markers were found to be significantly higher in the ACS group than the controls. The difference also continued in subgroup analyzes. NLR and PLR correlated with many other ACS indicators.Key words: Platelet lymphocyte ratio, neutrophil lymphocyte ratio, acute coronary syndrome, troponin. Abstract

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Section: Discussionsupporting

confidence: 58%

Correlations between hematological indicators and other known markers in acute coronary syndromes

Ertürk¹,

Çağlar²,

Bıyık³

2017

ejcm

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“…Moreover, growing interest has been directed towards leukocyte subtypes and especially the neutrophil-to-lymphocyte ratio (NLR), an inexpensive and convenient way to identify inflammatory parameters, and potentially an even more accurate indicator of cardiovascular risk than absolute blood cell counts [11,12].…”

Section: Introductionmentioning

confidence: 99%

Impact of diabetes on neutrophil-to-lymphocyte ratio and its relationship to coronary artery disease

Verdoia¹,

Schaffer²,

Barbieri³

et al. 2015

Diabetes & Metabolism

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“…17 More recently, attention has shifted to leukocyte subtypes and to the neutrophil to lymphocyte ratio (NLR), potentially being more accurate and stable than absolute blood cell counts, especially in patients with acute presentation, where it has been associated with clinical outcome and procedural results after percutaneous revascularization. 18,19 However, few reports have evaluated the relationship between NLR and the prevalence and extent of CAD; this was the aim of the present study.…”

Section: Introductionmentioning

confidence: 99%

Neutrophil to Lymphocyte Ratio and the Extent of Coronary Artery Disease

et al. 2015

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The neutrophil to lymphocyte ratio (NLR), an inflammatory biomarker, may be of predictive and prognostic value for cardiovascular (CV) events. We evaluated the relationship of NLR with the prevalence and extent of coronary artery disease (CAD) in consecutive patients undergoing elective or urgent coronary angiography. Our population (n ¼ 3738 patients) was divided into NLR quartiles. Higher NLR was associated with aging and established CV risk factors, previous percutaneous coronary revascularization, acute presentation, and more complex pharmacological therapy. The NLR was related to platelet count, white blood cell count, creatinine, glycemia, uric acid, and C-reactive protein (all P ¼ .001) levels but inversely related to hemoglobin (P < .001), total cholesterol (P ¼ .005), and triglycerides (P < .001) levels. The NLR was associated with multivessel disease (P < .001), anterior descending, right coronary arteries (P < .001) or circumflex branch lesions (P ¼ .01), percentage of stenosis (P < .001), coronary calcification (P < .001), and intracoronary thrombus (P < .001) but inversely with in-stent restenosis (P < .001) and thrombolysis in myocardial infarction flow (P ¼ .04). The NLR was directly related to the prevalence of CAD (P ¼ .001) and severe CAD (P < .001). In patients undergoing coronary angiography, the NLR is independently associated with the prevalence and severity of CAD.

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Neutrophil to lymphocyte ratio predicts short- and long-term mortality following revascularization therapy for ST elevation myocardial infarction

Cited by 100 publications

References 30 publications

Correlations between hematological indicators and other known markers in acute coronary syndromes

Correlations between hematological indicators and other known markers in acute coronary syndromes

Impact of diabetes on neutrophil-to-lymphocyte ratio and its relationship to coronary artery disease

Neutrophil to Lymphocyte Ratio and the Extent of Coronary Artery Disease

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