Neutrophil-to-Lymphocyte Ratio Predicts the Severity of Incarcerated Groin Hernia

Xie, Xiaoxiao; Feng, Shu; Tang, Zhongling; Chen, Longyu; Huang, Yongsheng; Yang, Xianzhi

doi:10.12659/msm.905728

Cited by 33 publications

(32 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 10 ] Recent studies also generalize the application of NLR to the field of hernia surgery and it was be found to be significantly associated with persistent postsurgical pain bowel, [ 11 ] the presence of a strangulated inguinal hernia, [ 12 ] and bowel resection in incarcerated groin hernia patients. [ 13 ]…”

Section: Introductionmentioning

confidence: 99%

Pre-surgical peripheral blood inflammation markers predict surgical site infection following mesh repair of groin hernia

Zhuo¹,

D²,

Chen

et al. 2021

Medicine

View full text Add to dashboard Cite

Surgical site infection (SSI) is a costly postoperative complication with a decrease in the quality of life. We aimed to probe the predictive role of peripheral blood inflammation markers for SSI following mesh repair of groin hernia (GH). This retrospective study assessed the data of 1177 patients undergoing elective mesh repair of GH (open/laparoscopy) in the absence of antibiotic prophylaxis. The relation between demographics, surgical factors, pre-surgical laboratory results and the occurrence of SSI were investigated by univariate and multivariate analyses. Receiver operating characteristic analysis was performed to determine the optimal threshold of parameters and compare their veracity. The overall SSI rate was 3.2% with 1-year follow-up (38 superficial and 1 deep SSI). Patients with SSI had significant higher pre-surgical neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) than those without ( P = .029 and P = .045, respectively); their NLR and PLR correlated positively with postoperative total days of antibiotic treatment for SSI (r = .689, P = .000; r = .493, P = .001; respectively). NLR and PLR had larger areas under the receiver operating characteristics curves than neutrophil (.875 vs. .601; P = .000; .726 vs. .601; P = .017). The combination of PLR and neutrophil/NLR raised the predictive sensitivity of PLR for SSI (sensitivity: PLR: 74.36%; PLR + neutrophil: 82.05%; PLR + NLR: 83.57%). On multivariate analyses, higher preoperative NLR (cut-off 2.44) and PLR (cut-off 125.42) were independent predictors for SSI. Higher pre-surgical NLR and PLR may be valuable predictors for SSI following elective mesh repair of GH.

show abstract

Section: Introductionmentioning

confidence: 99%

Pre-surgical peripheral blood inflammation markers predict surgical site infection following mesh repair of groin hernia

Zhuo¹,

D²,

Chen

et al. 2021

Medicine

View full text Add to dashboard Cite

show abstract

“…Apart from this, there are studies showing that there is an increased risk of small bowel resection in patients who are of female gender, [14][15][16] are of advanced age (>65), [14,17] have a long duration of incarceration, [15,[18][19][20] presence of bowel obstruction, [15,18,19] and an apparent peritonitis tableux. [15] Unlike in the studies mentioned above, in this study, it was observed that female gender and older age do not increase the risk of bowel resection.…”

Section: Discussionmentioning

confidence: 99%

“…When we looked at from the perspective of laboratory diagnostic methods, there are studies that assert that increased WBC count, [15,[18][19][20] increased neutrophil count [15,20] and increased NLR ratio, [18] increase the risk of small bowel resection. In all of these studies, comparisons were made according to whether there was a small bowel resection or not.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Role Of The Lactate Level In Determining The Risk Rates Of Small Bowel Resection In Incarcerated Hernias

Şahin¹,

Buluş²,

Yavuz³

et al. 2020

Ulus Travma Acil Cerrahi Derg

View full text Add to dashboard Cite

BACKGROUND: An incarcerated hernia is a part of the intestine or abdominal tissue that becomes trapped in the sac of a hernia. An increase in morbidity and mortality occurs after intestinal resections from strangulated hernias. This study aims to examine the markers that may be effective in determining the risk of small bowel resection due to incarcerated hernias. In particular, we aimed to investigate the effect s of blood lactate levels in determining this risk. METHODS:A cross-sectional retrospective study was designed. Patients, whose preoperative diagnosis were reported as incarcerated hernia and had essential information, were included in this study. They were divided into two groups according to whether they had resection or not. Age, gender, hernia type, hernia side, resection material, blood lactate level (BLL), white blood cell (WBC), neutrophil count (NE), lymphocyte count (LY), neutrophil/lymphocyte ratio (NLR), platelet count (PLT), lactate dehydrogenase (LDH), radiologic bowel obstruction sign and comorbidities were evaluated. RESULTS:Sixty-seven patients were included in this study. It was observed that 16 (23.9%) of these patients underwent small intestinal resection, 16 (23.9%) had an omentum resection, while no resection was performed on 35 (52.2%) patients. There was a statistically significant difference regarding radiologically intestinal obstruction (p=0.001), hernia type (p=0.005), BLL (p<0.001), WBC, NLR and LDH values (p<0.05). In incarcerated hernia patients with a lactate value ≥1.46 mg/dL, sensitivity was observed to be 84.0% and specificity 86.0% (p<0.001). CONCLUSION:In patients with a preliminary diagnosis of an incarcerated hernia, the risk of possible small bowel resection is the most important point in deciding for an operation. The presence of an intestinal obstruction in radiological examinations, and particularly the high levels of WBC, NLR, LDH and BLL, may indicate a necessity for possible small bowel resection. Concerning the risk associated with small bowel resection, blood lactate levels ≥1.46 mg/dL may be alerting.

show abstract

“…Neutrophil-lymphocyte ratio (NLR) and plateletlymphocyte ratio (PLR) can be a good predictor of the severity of inflammatory response [10][11][12][13]. High NLR and PLR levels can be used as a marker to estimate intestinal necrosis and the need for intestinal resection in patients who will undergo surgery for OH [11,12].…”

Section: Discussionmentioning

confidence: 99%

Prognostic Factors in Obturator Hernia

2020

Signa Vitae

View full text Add to dashboard Cite

Objective: Obturator hernia is a rare type of hernia that can occur in the octogenarian patients. We discuss the diagnosis, treatment and management of patients with obturator hernia, and describe the clinical presentation, laboratory and radiological findings. Material and methods: A retrospective study was performed in ten patients diagnosed with an obturator hernia between December 2008 - 2019 at a single tertiary hospital. Patients’ demographic features, clinical symptoms, laboratory and imaging data, comorbidities, surgical treatment methods, postoperative morbidity and mortalities were evaluated. Results: The patients’ mean age was 84.4 years (range between 81 - 89 years). All patients presented with symptoms of small bowel obstructions; abdominal pain located in the lower quadrant (100%), vomiting (60%), nausea (80%) and distension (60%). All patients had air-fluid levels on X-ray. We performed small intestine resection and an end to end anastomosis in four patients, resection with ileostomy in two patients and bowel reduction in four patients. Postoperatively, an anastomosis leak occurred in two patients, they were re-operated and an ileostomy was performed. In the post-op period, six patients died, and four patients survived. Conclusion: Obturator hernia is seen in octogenarian patients with symptoms of small bowel obstruction. The diagnosis is based mostly on computed tomography findings. An elevated neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and lactate levels can be used as a biomarker for the prediction of non-viable small bowel in these OH patients.

show abstract

Neutrophil-to-Lymphocyte Ratio Predicts the Severity of Incarcerated Groin Hernia

Cited by 33 publications

References 16 publications

Pre-surgical peripheral blood inflammation markers predict surgical site infection following mesh repair of groin hernia

Pre-surgical peripheral blood inflammation markers predict surgical site infection following mesh repair of groin hernia

The Role Of The Lactate Level In Determining The Risk Rates Of Small Bowel Resection In Incarcerated Hernias

Prognostic Factors in Obturator Hernia

Contact Info

Product

Resources

About