Neutrophilic figurate erythema of infancy associated with juvenile myelomonocytic leukemia

Puerto, Constanza del; Tuma, M. Curi; Bombardière, Sergio González; Silva-Valenzuela, S.

doi:10.1016/j.adengl.2015.05.001

Cited by 2 publications

(2 citation statements)

References 11 publications

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“…Only rare reports exist of Sweet syndrome occurring in children with leukemia, most commonly acute myelogenous leukemia, and are even rarer in JMML. [2][3][4] Leukemia cutis in children is extremely uncommon and is most often associated with acute myeloid leukemia followed by acute lymphoblastic leukemia. The median age at presentation is approximately 2 years, and lesions present commonly as erythematous-to-violaceous nodules or papules occurring on the head and lower limbs.…”

Section: Discussionmentioning

confidence: 99%

Leukemia cutis in a child with juvenile myelomonocytic leukemia presenting with Sweet syndrome–like lesions and a history of multiple juvenile xanthogranulomas

et al. 2020

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Section: Discussionmentioning

confidence: 99%

Leukemia cutis in a child with juvenile myelomonocytic leukemia presenting with Sweet syndrome–like lesions and a history of multiple juvenile xanthogranulomas

et al. 2020

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“…While it appears reasonable to consider NFEI as a benign chronic condition, a recent case report by Del Puerto Troncoso et al had a cautionary message . They published the case of a 2‐year‐old girl with a 3‐month history of asymptomatic annular erythematous skin lesions.…”

Section: Discussionmentioning

confidence: 99%

Neutrophilic figurate erythema of infancy: A diagnostic challenge

2018

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Neutrophilic figurate erythema of infancy (NFEI) is a rare variant of annular erythema of infancy. It is characterized by annular erythematous plaques, occasionally with a polycyclic configuration. The main challenge is to differentiate this rare entity from other figurate erythemas associated with serious diseases such as neonatal lupus erythematosus. We present the case of a 9‐month‐old female admitted with a skin rash of unclear etiology. The rash started on her face at the age of 3 months and gradually spread to her extremities. She had no constitutional symptoms, and her health and development were otherwise unremarkable since birth. This persistent skin eruption consisted of many ill‐defined erythematous papules and annular plaques. Histologic examination revealed perivascular neutrophils and eosinophils with abundant nuclear dust without signs of vasculitis. NFEI is a diagnostic enigma both clinically and histologically. Absence of an underlying cause, dermal neutrophilic infiltrate with leukocytoclasis, and lack of vascular damage are the keys to diagnosis.

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Neutrophilic figurate erythema of infancy associated with juvenile myelomonocytic leukemia

Cited by 2 publications

References 11 publications

Leukemia cutis in a child with juvenile myelomonocytic leukemia presenting with Sweet syndrome–like lesions and a history of multiple juvenile xanthogranulomas

Leukemia cutis in a child with juvenile myelomonocytic leukemia presenting with Sweet syndrome–like lesions and a history of multiple juvenile xanthogranulomas

Neutrophilic figurate erythema of infancy: A diagnostic challenge

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