Nevus of Ota: The Unusual Birthmarks: A Case Report

Abstract

Nevus of Ota is a benign congenital melanosis bulbi. It is a rare entity, commonly seen in female. It occurs among Asians and Africans. It mainly involves the eye, skin and ear. It is predominantly unilateral but could be bilateral. Typical clinical manifestation was present in our case, however, biopsy is the investigation of choice. There is no specific treatment but ophthalmological and dermatological intervention can be opted. Outcome is remarkably good. Here we reported a case of a child with Nevus of Ota who was primarily admitted at paediatric department with enteric fever. We managed her conservatively and followed up in specific department.
 Bangladesh J Child Health 2020; VOL 44 (1) :60-63

A 39-Year-Old Woman with Oculodermal Melanocytosis: A Case Report

“…As many as 50% of hyperpigmentation due to an increase in the number of melanocytes occurs at birth with macular pigmentation, which is usually localized in the forehead and periocalar region of the distribution region of the ophthalmic and mandibular branches of the trigeminal nerve 2,5. Oculodermal melanocytosis (ODM) affects 0.014% -0.034% of the Asian population and is more common in Women up to 85%, generally occurs unilaterally as in these patients 2. Several pathological theories have been put forward, such as that melanocytes have not completely migrated from the neural crest to the epidermis at the embryonic stage.…”

“…Migration of hair bulb melanocytes and reactivation of pre-existing latent dermal melanocytes, triggered by dermal inflammation, ultraviolet radiation cannot reach the deep dermal melanocytes or hormonal changes during pregnancy.According to the Mishima classification, she was classified to type II, namely, moderate gray intensity with involvement of the eyelids, zygomatic area, and bridge of the nose. Skin biopsy is necessary only if clinical changes are suspected in the form of malignant transformation of the skin, eyes, and mucosal tissue 2. The patient complains that the left eye is rolling inward, resulting in esotropia 45 o of the eyeball, indicating the possibility of a muscle disorder or nerve disorder, and this will be proven by further examination.…”