New 13-vinyl derivatives of berberine: synthesis and characterization

Демехин, Олег Д.; Буров, Олег Н.; Клецкий, М. Е.; Лисовин, Антон В.; Курбатов, С. В.; Березняк, Елена Александровна; Тришина, А. В.

doi:10.1007/s10593-022-03067-w

Cited by 3 publications

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“…31 Nucleophilic addition at the C-ring or nucleophilic substitution of the methoxy group in the D-ring are commonly employed for structural modification of berberine. Successful approaches, including those developed by our group, [32][33][34][35][36] involve umpolung strategies. 37 These approaches enable the reduction of the C-ring, followed by the use of electrophilic reagents to attack the C and D rings 10,29,[38][39][40][41] (Scheme 1).…”

Section: Introductionmentioning

confidence: 99%

Optimal synthesis conditions for NBF-modified 8,13-dihydroberberine derivatives

Zagrebaev,

Butova,

Guda

et al. 2024

New J. Chem.

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Section: Introductionmentioning

confidence: 99%

Optimal synthesis conditions for NBF-modified 8,13-dihydroberberine derivatives

Zagrebaev,

Butova,

Guda

et al. 2024

New J. Chem.

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A Structural Modification of Berberine Using CH Acids and Ethoxyethylenes Based on Them

Демехин

Буров²,

Клецкий³

et al. 2022

Chem Heterocycl Comp

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The chemistry of heterocycles in the 21st century

Charushin,

Verbitskiy,

Chupakhin

et al. 2024

RUSS CHEM REV

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The chemistry of heterocyclic compounds has traditionally been and remains a bright area of chemical science in Russia. This is due to the fact that many heterocycles find the widest application. These compounds are the key structural fragments of most drugs, plant protection agents. Many natural compounds are also derivatives of heterocycles. At present, more than half of the hundreds of millions of known chemical compounds are heterocycles. This collective review is devoted to the achievements of Russian chemists in this field over the last 15–20 years. The review presents the achievements of leading heterocyclists representing both RAS institutes and university science. It is worth noting the wide scope of the review, both in terms of the geography of author teams, covering the whole of our large country, and in terms of the diversity of research areas. Practically all major types of heterocycles are represented in the review. The special attention is focused on the practical applications of heterocycles in the design of new drugs and biologically active compounds, high-energy molecules, materials for organic electronics and photovoltaics, new ligands for coordination chemistry, and many other rapidly developing areas. These practical advances would not be possible without the development of new fundamental transformations in heterocyclic chemistry.<br> Bibliography — 2237 references.

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New 13-vinyl derivatives of berberine: synthesis and characterization

Cited by 3 publications

References 24 publications

Optimal synthesis conditions for NBF-modified 8,13-dihydroberberine derivatives

Optimal synthesis conditions for NBF-modified 8,13-dihydroberberine derivatives

A Structural Modification of Berberine Using CH Acids and Ethoxyethylenes Based on Them

The chemistry of heterocycles in the 21st century

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