2002
DOI: 10.1055/s-2002-33786
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New Alloaromadendrane, Cadinene and Cyclocopacamphane Type Sesquiterpene Derivatives and Bibenzyls from Dendrobium nobile

Abstract: Five new sesquiterpene glycosides with alloaromadendrane, cadinene and cyclocopacamphane type aglycones, one new cyclocopacamphane type sesquiterpene, two new bibenzyls and eight known compounds have been obtained from stems of Dendrobium nobile Lindl. Their structures were determined on the basis of 1D, 2D NMR and HR-MS analyses and chemical methods.

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Cited by 77 publications
(45 citation statements)
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“…20) Determination of Absolute Configuration The concentrated residue of the hydrolyzed sugars in pyridine (0.04 mol/l) and L-cysteine ethyl ester hydrochloride (0.06 mol/l) were mixed and the solution was warmed at 60°C for 1 h. Acetic anhydride (150 ml) was then added and the mixture was warmed at 90°C for another 1 h. After evaporation of pyridine and acetic anhydride in vacuo, each residue was dissolved in acetone (350 ml) and the solution (1 ml) was subjected to GC. 21) The peaks for peracetylated thiazolidine derivatives with retention time of 31.68 and 44.57 min were observed for the samples which were, respectively, identical to the derivatives of authentic Dglucose and L-rhamnose prepared in the same manner.…”
Section: Methodsmentioning
confidence: 63%
“…20) Determination of Absolute Configuration The concentrated residue of the hydrolyzed sugars in pyridine (0.04 mol/l) and L-cysteine ethyl ester hydrochloride (0.06 mol/l) were mixed and the solution was warmed at 60°C for 1 h. Acetic anhydride (150 ml) was then added and the mixture was warmed at 90°C for another 1 h. After evaporation of pyridine and acetic anhydride in vacuo, each residue was dissolved in acetone (350 ml) and the solution (1 ml) was subjected to GC. 21) The peaks for peracetylated thiazolidine derivatives with retention time of 31.68 and 44.57 min were observed for the samples which were, respectively, identical to the derivatives of authentic Dglucose and L-rhamnose prepared in the same manner.…”
Section: Methodsmentioning
confidence: 63%
“…For the cyclopacamphane-type sesquiterpene in Dendrobium species, C-3 is usually a quaternary carbon without oxygen and C-15 is constantly a methyl or an oxygenated methylene. [5][6][7] Interestingly, an oxygenated quaternary carbon (δ C 78.1) and a methylene carbon (δ C 35.2) signals appeared in 13 C NMR (DEPT) spectrum of compound 1. From the HSQC spectral data of 1, twenty-one protons were assigned unambiguously to thirteen carbons, respectively.…”
Section: Resultsmentioning
confidence: 99%
“…Indeed, noble dendrobium is one of the easiest orchids to grow (CAMPOS, 1998;SILVA, 1986). It is one of the three species used in the formulation of "ShiHu" (with D. tosaense and D. moniliforme) (LO et al, 2004;YE and ZHAO, 2002), which is an antipyretic and tonic drink that is also described as an aphrodisiac in traditional Chinese medicine (HANELT, 2001). It also has antitumor and antimicrobial properties and inhibition of in-vitro lipid peroxidation (DEVI et al, 2009), and anti-retroviral (HIV) properties (SÁNCHEZ-DUFFHUES et al, 2008).…”
Section: Introductionmentioning
confidence: 99%