New amidophosphine-phosphinites (tLANOPs) as chiral ligands for asymmetric hydrogenation reactions

A [Pd (η3‐PhCHCHCHPh)(phosphino‐oxazoline)]+ complex with almost identical P‐ and N‐trans influences. 13C chemical shifts and allylic alkylation chemistry

“…There are a number of catalytic reactions for which 'meta-dialkyl effects' have been shown to be useful. 16 We observed earlier 14b that the ee in the Pd-catalysed allylic alkylation in Eqn (1) increases from ca 91% with 3 as auxiliary to ca 97% with 4. We report here that, surprisingly, the ee sinks to ca 66% with 5, and offer an explanation for this observation based on detailed NMR studies.…”

Iridium‐Catalyzed Enantioselective Hydrogenation of Imines with Xylose Diphosphite and Diphosphinite Ligands

“…[10,11] An example of the use of an amidophosphine-phosphinite ligand is reported for the hydrogenation of cyclic iminium salts. [12] However, as far as we know, no diphosphite ligands are reported that provide enantioselectivity in the asymmetric hydrogenation of imines.…”

Asymmetric transfer hydrogenation of acetophenone derivatives with novel chiral phosphinite based η6-p-cymene/ruthenium(II) catalysts

“…The IR spectra were recorded on a Mattson 1000 ATI UNICAM FT-IR spectrometer as KBr pellets. 1 H (400.1 MHz), 13 C NMR (100.6 MHz) and 31 …”

“…After addition of dry toluene, the white precipitate (triethylammonium chloride) was filtered off under argon and dried in vacuo to produce a white viscous oily compound 2 (Yield: 273 mg, 99%). 31 …”