New and Facile Synthesis of Substituted Pyrrole, Pyridine, Pyrazolo[4,3-b] Pyridine, Pyrano[3,2-c] Quinoline,  Napthopyran, Naphthodipyran and  Coumarin Derivatives

El‐Taweel, F. M. A.; Elagamey, A. A.

doi:10.4236/ijoc.2013.31007

Cited by 6 publications

(1 citation statement)

References 8 publications

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“…Thus, structures 6 were established for the reaction products based on 1 H-NMR spectra which revealed the presence of pyran-4H protons at δ = 4.5-5.0 ppm. Compounds 6 were assumed to be formed via addition of quinolinyl C-3 to the π-deficient center in 2 to give the adduct 4, which hyrolysed and readily eliminate its acetyl group under the reaction conditions to give the intermediates 5.These were cyclised to 6.Elimination of the acetyl groups in this reactions parallels the reported deacetylation of similar systems under similar conditions [12][13][14][15]. Compounds 1 may be existing as 4quinolone [12][13][14][15], at which quinolin-3-position becomes more acidic than its acetyl group.…”

Section: Chemistrymentioning

confidence: 72%

Studies on Quinolin-2(1H)-One Derivatives: Synthetic Access to Pyrano[3,2-c] Quinoline and 3-Substituted Quinoline Derivatives

El‐Taweel

2013

ACSJ

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Section: Chemistrymentioning

confidence: 72%

Studies on Quinolin-2(1H)-One Derivatives: Synthetic Access to Pyrano[3,2-c] Quinoline and 3-Substituted Quinoline Derivatives

El‐Taweel

2013

ACSJ

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Synthetic Routes to Selected Heterocycles Containing Antipyrine Moiety

El‐Taweel

Elmaaty

2015

Journal of Heterocyclic Chem

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This review deals with the synthetic potentiality and utility of antipyrine and its derivatives in the synthesis of 4-substituted antipyrine and other heterocycles containing antipyrine moiety such as thiazole, pyrazolopyridines, pyrazolopyrimidines, and pyrazolotriazines. The reactions that cover the methods of synthesizing the aforementioned heterocycles such as addition, condensation, and cyclization were also reviewed.

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Derivational, Structural, and Biological Studies of Some New Pyrazolyl, Isoxazolyl, Pyrimidinyl, Pyridazinyl, and Pyridopyridazinyl from 4‐Substituted Antipyrine

Fadda

Rabie

Bondock

et al. 2016

Journal of Heterocyclic Chem

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(1,5‐Dimethyl‐3‐oxo‐2‐phenyl‐2,3‐dihydro‐1H‐pyrazol‐4‐yl)carbono‐hydrazonoyl dicyanide was used as a key intermediate for the synthesis of novel pyrazole, isoxazole, pyrimidine, and pyridazine derivatives. The newly synthesized compounds were characterized by elemental analyses and spectral data (IR, 1H‐NMR, 13C‐NMR, and mass spectra). The compounds were tested for their in vitro antibacterial activity against Gram‐positive bacteria as (Staphylococcus aureus and Bacillus subtilis) and Gram‐negative bacteria (Pseudomonas aeruginosa and Escherichia coli). The investigated compounds were tested against two strains of fungi Botrytis fabae and Fusarium oxysporum using diffusion agar technique. The biological results showed clearly that most of the synthesized compounds revealed mild to moderate activity against the used microorganisms.

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New and Facile Synthesis of Substituted Pyrrole, Pyridine, Pyrazolo[4,3-b] Pyridine, Pyrano[3,2-c] Quinoline, Napthopyran, Naphthodipyran and Coumarin Derivatives

Abstract: ABSTRACT

Cited by 6 publications

References 8 publications

Studies on Quinolin-2(1H)-One Derivatives: Synthetic Access to Pyrano[3,2-c] Quinoline and 3-Substituted Quinoline Derivatives

Studies on Quinolin-2(1H)-One Derivatives: Synthetic Access to Pyrano[3,2-c] Quinoline and 3-Substituted Quinoline Derivatives

Synthetic Routes to Selected Heterocycles Containing Antipyrine Moiety

Derivational, Structural, and Biological Studies of Some New Pyrazolyl, Isoxazolyl, Pyrimidinyl, Pyridazinyl, and Pyridopyridazinyl from 4‐Substituted Antipyrine

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