New approach to the treatment of adolescent hip dysplasia

Huang, Shibo; Zhao, Dewei; Yang, Lei

doi:10.1016/j.mehy.2013.04.005

Cited by 2 publications

(3 citation statements)

References 15 publications

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“… 11 The grade of dislocation and the hip joint surrounding the soft tissue contracture often become more obvious. 12 , 13 It has been reported that it is difficult to achieve satisfactory development of the acetabulum in reductions undertaken after 18 months of age. 14 The developmental potential of an acetabular shape can last until the patient is 10 years old.…”

Section: Discussionmentioning

confidence: 99%

“…16 Their parents usually seek medical advice at around 12 months of age following abnormal movements, which leads to more infants with DDH being diagnosed from 12 to 18 months of age in China. 16 Hip development ability in infants under 18 months of age is rather strong, 12 , 15 so it is advisable to adopt a minimally-invasive conservative treatment. In this present study, dynamic casting for the hip joint was applied for patients with DDH aged 12–18 months at diagnosis with satisfactory outcomes.…”

Section: Discussionmentioning

confidence: 99%

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Dynamic long leg casting fixation for treating 12- to 18-month-old infants with developmental dysplasia of the hip

Cai

Zhang

et al. 2016

J Int Med Res

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ObjectiveTo evaluate the effect of dynamic long leg casting in paediatric patients with developmental dysplasia of hip (DDH) diagnosed at 12–18 months.MethodsThe adductor tenotomy, closed reduction, and dynamic long leg casting method was adopted to treat paediatric patients with DDH. The hips were divided into four groups according to the Tonnis radiographic dislocation classification. Groups were also classified according to the baseline acetabular index (AI): 30°–35°, 36°–40°, and > 40°. The outcomes of the reductions were evaluated according to McKay’s hip function criteria and Severin’s radiological criteria.ResultsA total of 246 patients (339 hips) had complete follow-up data. After 3 months of orthosis fixation, the results were satisfactory in 264 hips (77.88%). Hip function was rated as ‘excellent’ or ‘good’ in 43 of 51 (84.31%) Tonnis type 1 hips, 125 of 155 (80.65%) type 2 hips, 70 of 90 (77.78%) type 3 hips, and 34 of 43 (79.07%) type 4 hips. The higher the baseline AI, the lower the rates of ‘excellent’ and ‘good’ hip function. Favourable radiological results (Severin types I and II) were found in 266 of 339 (78.47) hips.ConclusionsDynamic long leg casting is an effective method for treating patients with DDH aged 12–18 months at diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Dynamic long leg casting fixation for treating 12- to 18-month-old infants with developmental dysplasia of the hip

Cai

Zhang

et al. 2016

J Int Med Res

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“…One such factor is articular cartilage degeneration, which has been reported in early DDH. In addition, secondary osteoarthritis (OA) has also been shown to occur with high incidence in late stages of the disease (Huang et al, 2013). The mechanisms by which acetabular cartilage degeneration occurs in early DDH is not yet clear.…”

Section: Introductionmentioning

confidence: 99%

Correlation of acetabular chondrocyte apoptosis with caspase-3 and Bcl-2 expression in developmental dislocations of the hip

Ding

Liu

et al. 2016

Genet. Mol. Res.

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ABSTRACT. This study aimed to determine whether abnormal apoptosis is present in acetabular cartilage in early developmental dislocations of the hip (DDH), and if so, whether it is correlated with the expression of caspase-3 and Bcl-2. DDH was induced in 24 4-week-old New Zealand white rabbits. Acetabular cartilage specimens from the experimental and control groups were stained with hematoxylin and eosin (H&E). Animals from the experimental group developed acetabular dysplasia. Apoptotic chondrocytes were observed by ultrastructural electron microscopy and H&E. TUNEL assays revealed significantly greater acetabular chondrocyte apoptosis in the treated samples as compared to the control. Significantly higher caspase-3 expression and lower Bcl-2 expression were also measured in the DDH group compared with the control. We conclude that excessive apoptosis does occur in acetabular cartilage with DDH, and is positively correlated with high caspase-3 expression as well as low Bcl-2 expression.

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New approach to the treatment of adolescent hip dysplasia

Cited by 2 publications

References 15 publications

Dynamic long leg casting fixation for treating 12- to 18-month-old infants with developmental dysplasia of the hip

Dynamic long leg casting fixation for treating 12- to 18-month-old infants with developmental dysplasia of the hip

Correlation of acetabular chondrocyte apoptosis with caspase-3 and Bcl-2 expression in developmental dislocations of the hip

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