Summary
Serial assays of oestrone, oestriol, pregnanediol and chorionic gonadotrophin have been made in maternal urine from 32 weeks gestation until delivery in rhesus immunized patients whose infants suffered from haemolytic disease o varying severity. The results were compared with those from a series of normally pregnant women of comparable age and gestation period. In the rhesus patients no correlation could be demonstrated between severity of disease and endocrine profile. Assays of hormones and their metabolites were of little or no value in the management of patients with rhesus immunization.