New Automated Chemiluminescence Immunoassay for Simultaneous but Separate Detection of Human Immunodeficiency Virus Antigens and Antibodies

Performance of the Liaison XL Murex HIV Ab/Ag Test on Clinical Samples Representing Current Epidemic HIV Variants

“…Overall, our results confirm the excellent clinical sensitivity of Liaison XL HIV that was determined recently by Alonso et al (14). However, a major limitation of their paper was the absence of data about the ability of Liaison XL HIV to detect infections with different HIV variants.…”

“…A new 4th-generation assay, the DiaSorin (Saluggia, Italy) Liaison XL Murex HIV Ab/Ag (Liaison XL), was recently developed. However, few studies have investigated the performance of this assay (1,13,14), and no data are available about its ability to recognize different HIV variants, except for data about the p24 antigen (1).…”

Performance of Liaison XL automated immunoassay platform for blood‐borne infection screening on hepatitis B, hepatitis C, HIV 1/2, HTLV 1/2 and Treponema pallidum serological markers

“…This assay platform has recently been evaluated concerning the assays for HBsAg, anti‐HCV and HIV Ag/Ab (Alonso et al , ; Krawczyk et al , ; Lemee et al , ). In addition, a study on operative performance and efficiency of this assay platform has been conducted elsewhere (Fruttero et al , ).…”

“…Recently, a new platform has been introduced on the market, the LIAISON® XL chemiluminescence (CLIA) analyser (DiaSorin S.p.A, Vercelli, Italy), with a complete panel of assays for donor screening (Marquette & Blum, ; Alonso et al , ; Krawczyk et al , ; Lemee et al , ).…”

Chemiluminescence Immunoassay for the Detection of Antibodies against the 2C and 3ABC Nonstructural Proteins Induced by Infecting Pigs with Foot-and-Mouth Disease Virus

“…In recent years, CLIA has been shown to perform extremely well in diagnosing human diseases, such as human immunodeficiency virus (HIV) infection (14,15), cancer (based on the detection of tumor markers) (16), and hepatitis B (based on the detection of hepatitis B virus surface antigen [HBsAg]) (17,18), due to its high sensitivity, high signal-to-noise ratio, and wide linear range. To date, no reports of studies that used CLIA to detect FMDV infections have been published.…”