New Biomarkers for Cardiovascular Disease

Abstract

Cardiovascular disease is the leading cause of death and disability worldwide. Early detection and treatment of cardiovascular disease are crucial for patient survival and long-term health. Despite advances in cardiovascular disease biomarkers, the prevalence of cardiovascular disease continues to increase worldwide as the global population ages. To address this problem, novel biomarkers that are more sensitive and specific to cardiovascular diseases must be developed and incorporated into clinical practice. Exosomes are promising biomarkers for cardiovascular disease. These small vesicles are produced and released into body fluids by all cells and carry specific information that can be correlated with disease progression. This article reviews the advantages and limitations of existing biomarkers for cardiovascular disease, such as cardiac troponin and cytokines, and discusses recent evidence suggesting the promise of exosomes as cardiovascular disease biomarkers.

Study on the intervention effect of HCH integrated SMG health management model on community high-risk group of cardiovascular disease

“…Extensive epidemiological research has identified a multitude of risk factors, which can be classified into modifiable and non-modifiable categories. Non-modifiable risk factors, including age, sex, genetics, and race, are beyond individuals' control ( 4 , 11 , 12 ). Of particular significance, age serves as an unmodifiable risk factor for CVDs, as the likelihood of developing CVDs escalate with advancing age ( 13 ).…”

“…This study aims to compare the HCH model with the combined SMG model to comprehensively assess the strengths and weaknesses of different health management approaches. While the HCH model typically focuses on the continuity of care from healthcare institutions to homes and communities, the inclusion of SMG elements allows for further examination of the long-term impact of this model on patients' self-management abilities and health conditions ( 12 ). By conducting comparative research, differences among the models in patient engagement, health improvement outcomes, and healthcare resource utilization efficiency can be revealed, providing scientific evidence for policy-making and practical applications.…”

Xinnaotongluo liquid protects H9c2 cells from H/R-induced damage by regulating MDM2/STEAP3

“…With the improvement of people's living standard, cardiovascular disease has become a kind of disease threatening human health [1]. Studies have shown that the current incidence and mortality of cardiovascular diseases have exceeded malignant tumors, becoming the first incidence of disease [2]. More than 5 million people die of cardiovascular disease each year, and the age of onset is trending younger.…”

Gene Expression Analysis Reveals Clinically Significant Genes Associated with Familial Hypercholesterolemia and Atherosclerosis

“…The genes, which exhibit varying degrees of activity under different circumstances, are examined to derive a functional profile of the group of genes. 15,16 In this study, we utilized networkanalyst.ca, a platform that employs limma to analyze the differential expression of genes in individuals with FH and atherosclerosis. Through analysis, we can identify the genes that have a key role in our specific ailment, offering a fresh perspective for diagnosis and study.…”