2024
DOI: 10.1101/2024.02.18.580890
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New, biomechanically sound tendon tissue after injection of uncultured, autologous, adipose derived regenerative cells in partial Achilles tendon defects in rabbits

Christoph Schmitz,
Christopher Alt,
Tobias Würfel
et al.

Abstract: BackgroundCurrent management options for partial tendon tears may not offer future potential to heal tissue and improve clinical results. This study tested the hypothesis that treatment of a partial rabbit common calcaneus tendon (CCT) defect with uncultured, autologous, adipose derived regenerative cells (UA-ADRCs) enables regenerative healing without scar formation, as recently observed in a biopsy of a human supraspinatus tendon.MethodsA full-thickness hole (diameter, 3 mm) was punched into the midsubstance… Show more

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