New butyrolactone and other metabolites from the bark of Endlicheria arenosa against of the phytopathogen Colletotrichum tamarilloi

Abstract

In this work, screening of Lauraceae species for their antifungal activity against Collectotrichum tamarilloi was carried out and the ethanol extract derived from the bark of Endlicheria arenosa was found to be the best candidate. From the ethanolic extract of the bark of E. arenosa, the hexane and chloroform fractions were found to be active, from these five fatty acids were identified and two lactones were isolated. The most active fatty acid was the dodecanoic acid with a minimal inhibitory concentration (MIC) of 78.0 μM. The butyrolactone 3R,4R-licunolide A, it has not previously reported, and licunolide B show both the lowest MIC (55.3 μM). This is the first report of compounds of natural origin as growth inhibitors of C. tamarilloi.

Colletotrichum Species Complexes Associated with Crops in Northern South America: A Review

“…Of these, 17 were conducted in Colombia, three in Venezuela, one in Ecuador, and two in Peru. The Colombian studies mainly performed agrochemicals evaluations [93] or in vitro evaluations of natural products, such as essential oils and metabolites obtained from plants [35,49,[94][95][96][97][98] and from microorganisms [42,[99][100][101]. In addition, we found an article evaluating the in vitro effect of a bacterium and its cell-free culture filtrate [27], an article evaluating resistance to anthracnose for plant breeding [32], and an article evaluating climatological conditions and the incidence of anthracnose [102].…”