Ore textures, epithermal open-space filling of Permian structures of the Alleghanian orogeny, and largely postorogenic mineralization of the Ellenville, New York, composite Zn Pb-Cu(Ag) vein system, provide permissive evidence for post-Permian mineralization. Isochron ages determined by 4~laser-fusion techniques for K-bearing liquid inclusions in main-stage quartz from the Ellenville deposit additionally suggest a Mesozoic time of mineralization, associated with extensional formation of the Newark basin. The best 4~ total-fusion age range is 165 + 30 to 193 _+ 35 Ma. The Mesozoic 4~age agrees with that of many other dated northern Appalachian Zn-Pb-Cu(Ag) deposits with near-matching lead isotope ratios, and adds new evidence of Jurassic tectonism and mineralization as an overprint to Late Paleozoic tectonism at least as far north as Ellenville (lat. 41~