New Chiral Organophosphorus Catalysts in Asymmetric Synthesis

Asymmetric Diels–Alder reaction with >C=P– functionality of the 2-phosphaindolizine-η1-P-aluminium(O-menthoxy) dichloride complex: experimental and theoretical results

“…Chiral phosphines constitute a very important group of ligands as their coordination compounds with transition metals have been extensively employed in asymmetric catalysis to convert achiral compounds into enantio-enriched products with high efficiency and enantioselectivity [5]. In many cases, chiral monophosphine ligands have been found to be more useful than chiral bisphosphines [6–8].…”

First DMAP-mediated direct conversion of Morita–Baylis–Hillman alcohols into γ-ketoallylphosphonates: Synthesis of γ-aminoallylphosphonates

“…Aminophosphonates and their derivatives [22–26] are thus recognized as promising compounds and a new class of drugs that are widely used in a variety of commercial applications. Indeed, they are known to influence various biochemical processes in plants, modifying or inhibiting them, or to have biological activities as for example antibiotics, antibacterial, anti-cancer or antithrombotic agents [22–26]. …”

Lanthanide‐Catalyzed Selective Addition of Diethyl Phosphite to Chalcones

“…The richness and diversity of organophosphorus compounds have made organophosphorus chemistry a subject of intense research over the last few decades. Accompanied by the increasing use of organophosphorus compounds in many different fields, including medicine, agriculture, organic optoelectronics, and homogeneous catalysis , much attention has been focused on efficient strategies to construct carbon–phosphorus bonds . Among the various routes reported, cross coupling of phosphorus agents with aryl halides or triflates and addition of phosphorus‐based nucleophiles (P‐nucleophiles) to activated carbon atoms are the most direct and efficient routes to form carbon–phosphorus bonds.…”