Introduction. There are several classifications of alveolar disease of the liver, but they do not provide complete information regarding all possible surgical interventions in terms of this pathology. Our study was aimed at identifying and structuring various approaches to staged surgical treatment of the disease, taking into account the current possibilities of minimally invasive surgery.Materials and methods. After carrying out a retrospective analysis of surgical treatment of 72 patients with alveolar disease of liver, we have developed a classification of the surgical interventions and 6 main staged approaches to surgical treatment for the disease. Results and discussion. The presented classification of surgical interventions for alveolar disease of the liver is entirely sufficient to divide all surgeries into the following groups: radical/ relatively-radical surgical interventions that make the patient free or nearly free of the disease, and palliative/diagnostic surgeries, that focus on alleviation of the patient’s condition. In addition, the volume and radicality of the liver resection as well as the drainage of the bile ducts and liver decay cavities can be clarified. Based on the developed classification of surgical interventions, we presented 6 main staged, case-centered approaches to the surgical treatment for liver alveolar disease and its complications.Conclusion. The presented classification of surgical interventions for alveolar disease of the liver is a way to explicitly divide the surgeries according to several criteria. Surgical treatment for alveolar disease of the liver includes various parts, which made it possible to develop 6 main options for a staged approach to surgical interventions, ensuring scientific and practical applications.