Vertical profiles of environmental and dew point temperature, atmospheric stability indices, and precipitable water (PW) derived from sounding data were analyzed for two radiosonde launch sites located 85 km apart in the State of São Paulo, Brazil. The objective of this study was to determine whether there is a correlation between radiosonde profiles and, particularly, whether the values of commonly used stability indices (K, TT, LI, SWEAT, CIN, and CAPE) and precipitable water (PW) determined for each location were similar. In addition, weather radar data were evaluated to determine the level of correlation between precipitation over the radiosonde launch sites and stability indices. Despite the small distance between the two sites, significant differences were found when these indices and PW were compared. Some of these differences can be explained by the fact that one launch site was located in a large metropolitan area and the other in a smaller city. The comparison of stability indices and PW with precipitation estimates from a weather radar suggested that there is a trend towards a correlation between these parameters. The results suggest that the extrapolation of upper-air sounding data, even at relatively small distance scales, may not always be appropriate.