New Compounds. 1, 1-Di-(p-chlorophenyl)-1,2,2,2-tetrachloroethane

Abstract

2) The Methobromide of ,3-Dimethylaminoethyl Salicylate.-The bromide I (36.8 g.), salicyloyl chloride (45 g., large excess) and dried benzene (75 8.) are heated on the water-bath until the evolution of gaseous hydrochloric acid ceases. The benzene is decanted, replaced by anhydrous acetone and the mixture boiled for one hour. This procedure is repeated and the solid phase subsequently recrystallized from alcohol as white prisms, m. p. 176', readily soluble in water, difficultly in alcohol; yield, 80%. Anal. Calcd. for ClzHlsOsNBr: Br, 26.3. Found: Br, 26.4.The corresponding iodide, prepared analogously from 11, forms, after recrystallization from alcohol, white needles, m. p. 147-148'; yield, 88%. Anal. Calcd. for CltH1801-NI: N,4.0; L36.2. Found: N,3.9; I, 36.0.

1:1:1-Trichloro-2:2-di-(p-chlorophenyl)ethane (DDT) and rat adipose tissue

“…1:1-Di-(p-chlorophenyl)-2:2-dichloroethyl-ene was prepared from DDT (Grumitt, Buck & Stearns, 1945). Di-(p-chlorophenyl) acetic acid was prepared from di-(p-chlorophenyl)dichloroethylene (Grumitt, Buck & Jenkins, 1945). 1:2:3:4:10:10-Hexachloro-6:7-epoxy-1:4:4a:5:6:7:8:8a-octahydro-1:4:5:8 -dimethanonaphthalene (Dieldrin), a gift of Shell Petroleum Co. Ltd., London, was recrystallized from ethanol.…”

Analysis and Properties of Bis-(p-chlorophenyl)methylcarbinol

“…The same procedure applied to (p-chlorophenyl)l.o-chlorophenyDmethylcarbinol gives 2,4'-dichlorobenzophenone, melt ing point 63-66°C ., in the theoretical yield. Similar oxidation of 1, l-bis-(p-chlorophenyl)-2,2-dichloroethviene derived from DDT has been used to establish the structure of DDT (9) and to analyze mixtures of isomeric DDT's (5).…”

Structural studies of polychlorinated hydrocarbons. V. 1,1,1,2-Tetrachloro-2,2-bis(p-chlorophenyl)ethane and 1,1,1-tribromo-2,2-bis(pchlorophenyl)ethane

“…14), 0ma x = 67°; 5612 independent reflections collected. (Grummitt, Buck & Jenkins, 1945). Colourless crystals were grown from aqueous isopropyl alcohol.…”