New Concept in Cranioplasty Based on Biomaterials Performance in Various Clinical Cases

Mohan, Dumitru; Nica, Dan Aurel; Mohan, Aurel George; Feder, Bogdan; Ciurea, Alexandru Vlad

doi:10.4028/www.scientific.net/kem.695.185

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Unfortunately, just several alloplastic materials like bioceramics, bone cements based on polymethylmetacrylate, and titanium represent an option at this moment for cranial reconstruction from biomaterials point of view. The ideal metallic biomaterial used for reconstruction should be light in weight, strong enough to resist to the mechanical stress and potential trauma, significantly malleable to allow alteration at surgery, chemically and biologically inert, non-carcinogenic and sterilisable [8,9,10,11].…”

Section: Introductionmentioning

confidence: 99%

Associated Titanium Mesh and Native Bone Cranioplasty in Posttraumatic Reconstruction of Frontal Skull Defects

Săceleanu

Tâlvan²,

Fagetan

et al. 2017

KEM

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Cranioplasty of frontal skull defects are used for cosmetic reasons, helping correct disfigurement, but also play a critical role in protecting intracranial content from exposure and compression. Modern surgical management is based on principles of craniofacial surgery such as early one-stage repair- if possible, exposure of all fracture fragments by well-sited cosmetic incisions, precise internal fixation and definitive soft tissue management. The choice of surgical approach depends on fracture severity, complexity, patient comorbidities, and surgeon preference and experience. In large skull defects, titanium mesh reconstruction offers good alternative to other biomaterials by eliminating the time consuming task of contour moulding. The aim of the study is to provide a comprehensive review of aesthetic and functional outcomes, involving titanium mesh implants associated with native bone reconstruction of frontal area posttraumatic defects. Also, the article is related to the authors own experience, in treating several patients with posttraumatic deformity of the frontal bone, assessing forehead contour aesthetics, pain, nerve function and late cerebral complications. A retrospective study was conducted using records from 14 adult patients, between 21-74 years of age, who underwent reconstruction of depressed frontal bone fractures, by receiving titanium mesh implants, between February 2013- October 2015. All patients had a minimum follow up of 5 months by clinical examination and periodic CT-scans. In order to evaluate the experimental results we follow different clinical parameters than late complications, like facial nerve function, cosmetic outcome, and pain. According our clinical results, titanium mesh is an effective method of forehead reconstruction, which provides predictably good long term results.

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Section: Introductionmentioning

confidence: 99%

Associated Titanium Mesh and Native Bone Cranioplasty in Posttraumatic Reconstruction of Frontal Skull Defects

Săceleanu

Tâlvan²,

Fagetan

et al. 2017

KEM

Self Cite

View full text Add to dashboard Cite

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Nanoparticles and Nanostructured Surface Fabrication for Innovative Cranial and Maxillofacial Surgery

et al. 2020

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A novel strategy to improve the success of soft and hard tissue integration of titanium implants is the use of nanoparticles coatings made from basically any type of biocompatible substance, which can advantageously enhance the properties of the material, as compared to its similar bulk material. So, most of the physical methods approaches involve the compaction of nanoparticles versus micron-level particles to yield surfaces with nanoscale grain boundaries, simultaneously preserving the chemistry of the surface among different topographies. At the same time, nanoparticles have been known as one of the most effective antibacterial agents and can be used as effective growth inhibitors of various microorganisms as an alternative to antibiotics. In this paper, based on literature research, we present a comprehensive review of the mechanical, physical, and chemical methods for creating nano-structured titanium surfaces along with the main nanoparticles used for the surface modification of titanium implants, the fabrication methods, their main features, and the purpose of use. We also present two patented solutions which involve nanoparticles to be used in cranioplasty, i.e., a cranial endoprosthesis with a sliding system to repair the traumatic defects of the skull, and a cranial implant based on titanium mesh with osteointegrating structures and functional nanoparticles. The main outcomes of the patented solutions are: (a) a novel geometry of the implant that allow both flexible adaptation of the implant to the specific anatomy of the patient and the promotion of regeneration of the bone tissue; (b) porous structure and favorable geometry for the absorption of impregnated active substances and cells proliferation; (c) the new implant model fit 100% on the structure of the cranial defect without inducing mechanical stress; (d) allows all kinds of radiological examinations and rapid osteointegration, along with the patient recover in a shorter time.

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New Concept in Cranioplasty Based on Biomaterials Performance in Various Clinical Cases

Cited by 2 publications

References 8 publications

Associated Titanium Mesh and Native Bone Cranioplasty in Posttraumatic Reconstruction of Frontal Skull Defects

Associated Titanium Mesh and Native Bone Cranioplasty in Posttraumatic Reconstruction of Frontal Skull Defects

Nanoparticles and Nanostructured Surface Fabrication for Innovative Cranial and Maxillofacial Surgery

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