Introduction: Branch retinal vein occlusion (BRVO), occurs at a retinal arteriovenous intersection, is a common cause of retinal vascular disease. The risk factors such as hypertension, arteriosclerosis, diabetes, smoking, hyperlipidemia, and glaucoma. BRVO affects males and females equally and occurs most frequently between the ages of 50 and 70. Vision loss from BRVO is typically due to macular ischemia, macular edema, or complications from neovascular disease Method: Reported a case of BRVO in a man, 50years-old with 10 years hypertension history, came to M.Djamil Hospital) with decreased vision of right eye since one month ago. Visual acuity right eye was 6/18 and visual acuity left eye was 6/6. aa:vv was 1:3,av crossing and venous tortuosity in superotemporal quadran. There was flame shape hemorrages and cotton-wool spot in same area. Foveal reflex was decreased. Central macular thickness was 466 µm on OCT. The management was injection bevacizumab intravitreal and then argon laser photocoagulation 3 weeks later. Result: After 3weeks, macular edema is decreased (234µm) and visual acuity improve up to +3lines of snellen chart (6/6). Conclusion: Combination of bevacizumab intravitreal injection as anti VEGF and laser photocoagulation on leakage area was effective in reducing of macular edema and visual acuity improvement.