The problem of non-fragile extended dissipative control design for a class of generalized neural networks (GNNs) with interval time-delay signals is investigated in this paper. By constructing a suitable Lyapunov-Krasovskii functional (LKF) with double and triple integral terms, and estimating their derivative by using the Wirtinger single integral inequality (WSII) and Wirtinger double integral inequality (WDII) technique respectively, and that is mixed with the reciprocally convex combination (RCC) approach. A new delay-dependent non-fragile extended dissipative control design for GNNs are expressed in terms of the linear matrix inequalities (LMIs). Then, the desired non-fragile extended dissipative controller can be obtained by solving the linear matrix inequalities (LMIs). Furthermore, a non-fragile state feedback controller is designed for GNNs such that the closed-loop system is extended dissiptive. Thus, the non-fragile extended dissipative controller can be adopted to deal with the non-fragile 2 − ∞ performance, non-fragile ∞ performance, non-fragile passive performance, non-fragile mixed ∞ and passivity performance, and non-fragile dissipative performance for GNNs by selecting the weighting matrices. Finally, simulation studies are demonstrated for showing the feasibility of the proposed method. Among them, one example was supported by the real-life application of the quadruple tank process system.