New cyclic tetranuclear copper(II) complexes containing quadrilateral cores: Synthesis, structure, spectroscopy and their interactions with DNA in aqueous solution

Giri, Gopal C.; Haldar, Shobhraj; Ghosh, A.; Chowdhury, Priyanka; Carrella, Luca M.; Ghosh, Utpal; Bera, Manindranath

doi:10.1016/j.molstruc.2017.04.033

Cited by 26 publications

(5 citation statements)

References 71 publications

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“…Earlier, this ligand is known to bind with copper(II) and nickel(II) ions to yield the mononuclear complexes that have been established by single crystal X‐ray crystallography . More recently, we have utilized the ligand HL for the synthesis of new cyclic tetranuclear copper(II) complexes containing quadrilateral cores showing DNA binding affinity in aqueous solution . Employing this ligand, we have also reported the coordination‐cum‐binding events of biologically relevant monosaccharides such as D‐glucose, D‐xylose and D‐mannose with new mononuclear iron(III) and zinc(II) complexes in aqueous solution .…”

Section: Resultsmentioning

confidence: 59%

Carboxylate Bridge Controlled Formation of Tetra‐ and Pentanuclear Nickel(II) Complexes: Synthesis, Crystal Structure, Spectroscopy and Magnetic Properties

et al. 2019

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A carboxyamine functionalized tridentate ligand in combination with three different carboxylate bridging groups (RCO 2 À ; R = CH 3 , C 2 H 5 and CF 3 ) has been utilized to prepare tetra-and pentanuclear nickel(II) complexes, [Ni 4 (CC 2 H 5 ) 2 (CH 3 OH) 2 ] (2) and [Ni 5 (L) 4 (μ 3 -OH) 2 (μ 1,3 -O 2 CCF 3 ) 2 ]Br 2 ⋅3H 2 O (3) (HL = 3-[(2-pyridylmethyl)-amino]-propionic acid). The complexes have been characterized using several techniques such as elemental analysis, solution electrical conductivity, FTIR and UV-Vis spectroscopy, and low temperature magnetic measurements. While complex 1 and 3 were further characterized using single crystal X-ray diffraction, molecular structure of complex 2 has been optimized using DFT calculation. Whereas the acetate/propionate groups deliver Ni 4 cluster, the trifluoroacetate group provides Ni 5 assembly. Molecular structures of complexes 1 and 2 comprise a central [Ni 4 O 6 ] core that could be described as a distorted face-shared dicubane with two missing vertices. On the other hand, the [Ni 5 (μ 3 -OH) 2 (μ 1,3 -O 2 CCF 3 ) 2 ] 6 + structural core of complex 3 contains five coplanar nickel(II) ions in a rectangular organization. Variable-temperature magnetic susceptibility studies reveal the interesting magnetic properties of complexes 1 and 3. While complex 1 shows both ferro-and antiferromagnetic interactions with J 1 = À 1.10 cm À 1 , J 2 = + 2.40 cm À 1 and J 3 = À 0.65 cm À 1 , complex 3 exhibits only ferromagnetic interactions with J 1 = + 2.0 cm À 1 and J 2 = + 1.0 cm À 1 .

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Section: Resultsmentioning

confidence: 59%

Carboxylate Bridge Controlled Formation of Tetra‐ and Pentanuclear Nickel(II) Complexes: Synthesis, Crystal Structure, Spectroscopy and Magnetic Properties

et al. 2019

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“…The most important coordination modes of the carboxylate groups are monodentate, syn‐syn bidentate, syn‐anti bidentate and anti‐anti bidentate [46,47] . In our laboratory, we have found that several di‐ and multinuclear Cu(II), Ni(II), Zn(II), Co(II) and Mn(II) complexes of carboxylate‐based multidentate ligands have exhibited the excellent binding interactions towards the biologically significant substrates such as DNA, BSA and different monosaccharides, in solution [48–54] . Recently, we have reported the synthesis, characterization, X‐ray crystal structure and phosphatase‐like activity of tetranuclear complexes of iron(III), zinc(II) and nickel(II) by utilizing carboxylate‐based multidentate ligands with appealing coordination chemistry [55,56] .…”

Section: Introductionmentioning

confidence: 94%

“…[46,47] In our laboratory, we have found that several diand multinuclear Cu(II), Ni(II), Zn(II), Co(II) and Mn(II) complexes of carboxylate-based multidentate ligands have exhibited the excellent binding interactions towards the biologically significant substrates such as DNA, BSA and different monosaccharides, in solution. [48][49][50][51][52][53][54] Recently, we have reported the synthesis, characterization, X-ray crystal structure and phosphatase-like activity of tetranuclear complexes of iron(III), zinc(II) and nickel(II) by utilizing carboxylate-based multidentate ligands with appealing coordination chemistry. [55,56] In this article, we report anthracene-appended carboxylate containing tridentate ligand, H 2 acpa which upon reaction with Cu((II), Mn(II) and Zn(II) salts, yields new mononuclear complexes, [Cu-…”

Section: Introductionmentioning

confidence: 99%

Cu(II), Mn(II) and Zn(II) Complexes of Anthracene‐Affixed Carboxylate‐Rich Tridentate Ligand: Synthesis, Structure, Spectroscopic Investigation and Their DNA Binding Profile

et al. 2022

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Anthracene-affixed carboxylate-rich tridentate ligand containing three new mononuclear complexes, [Cu(acpa)(H 2 O) 2 ]⋅H 2 O (1), [Mn(acpa)(H 2 O) 2 ] (2) and [Zn(acpa)(H 2 O) 2 ] (3) (H 2 acpa = 3-(anthracene-9-ylmethyl-carboxymethyl-amino)-propionic acid), have been synthesized and characterized by various analytical and spectral methods. In methanol, complexes 1-3 have been prepared by carrying out reaction of the ligand H 2 acpa with stoichiometric amounts of CuSO 4 ⋅ 5H 2 O, MnSO 4 ⋅H 2 O and ZnSO 4 ⋅ 7H 2 O respectively, in the presence of NaOH at ambient temperature. The X-ray crystal structure analysis reveals that complex 1 consists of a distorted square pyramidal copper center, coordinated to one acpa 2À ligand in a tridentate manner (N,O,O) and two exogenous water molecules. On the other hand, the molecular structures of complexes 2 and 3, optimized by DFT method indicate that their core arrangements around the metal centers are similar to that of 1. In solution, the coordination phenomena of Cu((II), Mn(II) and Zn(II) ions with the ligand H 2 acpa and the structural features of the complexes have been authenticated by UV-Vis and fluorescence titration experiments. The composition of the M II /acpa 2À complexes (M = Cu, Mn, Zn) in 1-3 has been observed to be 1 : 1, based on the UV-Vis/fluorescence titration results which are further supported by X-ray crystallography and DFT calculation. Complexes 1-3 are investigated for their binding affinity towards Calf Thymus (CT) DNA in solution at pH ∼ 7.5 by UV-Vis and fluorescence spectroscopic methods. From the electronic absorption spectral studies, it has been found that the DNA binding constants of 1-3 are (5.67 � 0.32) × 10 4 M À 1 , (2.35 � 0.26) × 10 4 M À 1 and (2.49 � 0.33) × 10 4 M À 1 , respectively, following the order 1 > 3 > 2. Measurements of viscosity of DNA in the absence and presence of the metal complexes suggest that all three complexes interact with DNA through partial intercalative mode.

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“…16,18,20,24 Although the synthesis of the transition metal-based binuclear and polynuclear compounds has been previously reported, there is a lack of research on synthesizing hybrid copper with different inorganic units using the same organic cations. [25][26][27][28] Previous research has demonstrated that the influence of inorganic units on the optical properties of hybrid halides is crucial. [16][17][18][19][20][21][22] However, limited research has been conducted to explore the differences in the optical properties of different Cu-X inorganic units.…”

Section: Introductionmentioning

confidence: 99%

Reversible tri-state structural transitions of hybrid copper(i) bromides toward tunable multiple emissions

Wu,

Qi,

Guo

et al. 2024

Inorg. Chem. Front.

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New cyclic tetranuclear copper(II) complexes containing quadrilateral cores: Synthesis, structure, spectroscopy and their interactions with DNA in aqueous solution

Cited by 26 publications

References 71 publications

Carboxylate Bridge Controlled Formation of Tetra‐ and Pentanuclear Nickel(II) Complexes: Synthesis, Crystal Structure, Spectroscopy and Magnetic Properties

Carboxylate Bridge Controlled Formation of Tetra‐ and Pentanuclear Nickel(II) Complexes: Synthesis, Crystal Structure, Spectroscopy and Magnetic Properties

Cu(II), Mn(II) and Zn(II) Complexes of Anthracene‐Affixed Carboxylate‐Rich Tridentate Ligand: Synthesis, Structure, Spectroscopic Investigation and Their DNA Binding Profile

Reversible tri-state structural transitions of hybrid copper(i) bromides toward tunable multiple emissions

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