New Daily Persistent Headache: Clinical Perspective

Abstract

New daily persistent headache is a recognized form of primary chronic daily headache. It is unique in its presentation and course. The goal of this article is to discuss the clinical characteristics, triggering factors, possible underlying pathogenesis and treatment options for this unique headache disorder. At present prognosis for new daily persistent headache is considered poor with very few effective treatment options. A new treatment paradigm for new daily persistent headache based on triggering events will be suggested. The current International Classification of Headache Disorders 2 criteria for new daily persistent headache will also be discussed including its apparent inadequacies and revised criteria will be recommended.

Is daily headache related to asthma? Results from a population-based survey

“…Considering that they experienced a daily headache for 2 weeks, the characteristic of the headache in our study might be similar to that of new daily persistent headache in chronic daily headache. New daily persistent headache is a rare disorder, with a prevalence of only 0.1% and pain occurred on 30/30 days unlike other forms in chronic daily headache [24][25][26]. Because the definition of headache in our study was not concordant with the diagnosis suggested by the International Classification of Headache Disorders, further studies are needed to identify the association between asthma and chronic daily headache in accordance with the definition in the International Classification of Headache Disorders.…”

“…In 2007, the Head-HUNT study found that headache in general, migrainous and non-migrainous, was related to asthma [13]. Moreover, asthma patients were found to be 3.2-fold more likely to have new daily persistent headache than individuals without asthma [19,20]. Although we found that asthma was related to daily headache in general, there is no explicit mechanism to explain this association.…”

“…The second limitation is that the prevalence of daily headache in our cohort was low, at only 0.9% of the population. However, the prevalence in our study might be correct because the prevalence of headache in our study might be similar to that of new daily persistent headache and prevalence of new daily persistent headache is low [24][25][26]. In addition, the prevalence of chronic daily headache is lower in Korea than the worldwide prevalence [21].…”

Refining clinical features and therapeutic options of new daily persistent headache: a retrospective study of 63 patients in India

“…The main controversy in the diagnostic criteria is regarding the presence of migrainous features [5]. ICHD-II acknowledges only one of photophobia, phonophobia, or mild nausea in primary NDPH.…”

The impact of triptan and doxycycline on neuroinflammatory biomarkers in acute migraine: study protocol of a randomized controlled trial

“…However, he only published one abstract on his open label use [26], no peer-reviewed paper, and referred to it in a recent review [27].…”