New Developments and Perspectives

Bakker, Frank C.; Eggink, Gerrit; Goessens, M. L. M. J.; Haarman, H. J. T. M.; Lefèvre, C.; Nen, D. Le; Segers, M.J.M.; Stapert, J. W. J. L.; Verbruggen, J.P.A.M.

doi:10.1007/978-3-642-56337-9_11

Practice of Intramedullary Locked Nails 2002

DOI: 10.1007/978-3-642-56337-9_11

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New Developments and Perspectives

Frank C. Bakker¹,

Gerrit Eggink²,

M. L. M. J. Goessens³

et al.

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Cited by 2 publications

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Morphological evaluation of the iliac and femoral arteries; possibilities and perspectives

Dziekiewicz

Markiewicz

Kozłowski

et al. 2014

Polish Journal of Surgery

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The study presented an approach to the morphometric image of atherosclerotic lesions of the final segment of the abdominal aorta, femoral and iliac arteries, considering possible endovascular intervention. The evaluation of these arteries is very important, because they are often used as a point of access for endovascular procedures performed on the peripheral arteries, or within the thoracic and abdominal aorta and its branches, as well as coronary arteries. the aim of the study was to determine morphometric measurements describing the atherosclerotic lesions, including the methodology of their surgical interpretation. Material and methods. The study group comprised 128 tomograms of patients qualified for surgery. An algorithm based on the mathematical morphology was designed to track the vessels, starting from the division of the common femoral artery, and ending at the bifurcation of the abdominal aorta. We proposed a set of numerical measurements of the observed arterial changes. Results and conclusions. We analysed 128 tomograms with a 94.5% efficiency, and with the assessment accuracy of the degree of lumen reduction (MAE-1.5%). We observed much higher measurement values of local tortuosity of the atherosclerotic arteries (0.3 -1 radians), as compared to their anatomical course in a healthy subject (0 -0.2 radians). The presented method can be a very accurate and useful tool in the numerical analysis of the lumen distribution of the arteries and atherosclerosis, dedicated to surgeons elaborating management strategies.

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Morphological evaluation of the iliac and femoral arteries; possibilities and perspectives

Dziekiewicz

Markiewicz

Kozłowski

et al. 2014

Polish Journal of Surgery

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Utility of an interferon-gamma release assay as a potential diagnostic aid for active pulmonary tuberculosis

Taki-Eddin

Monem

2011

J Infect Dev Ctries

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Introduction: Sensitivity, specificity, early confirmation and obtaining an optimal specimen are challenging problems in active tuberculosis (TB) diagnosis. Interferon-gamma release assay (IGRA) is a good indicator for latent TB but can it be useful as a diagnostic tool for active TB? This study was designed to address these challenges and assess the potential of IGRA as a diagnostic indicator of active pulmonary TB by comparing it with other MT diagnostic conventional methods and molecular methods. Methodology: The study was conducted on 91 patients with suspicion of pulmonary active TB. QuantiFERON-TB-Gold In-Tube, a commercial IFN-gamma assay, was compared with Ziehl Neelsen (ZN) smear, Lowenstein Jensen's (LJ) egg-based culture, and real-time polymerase chain reaction. The final clinical diagnosis was the standard comparator of the study. Results: Active pulmonary TB was confirmed in 48/91 (52.7%) patients. Sensitivity, specificity, positive predicted value (PPV), and negative predicted value (NPV) were 72.9%, 100%, 100%, 76.78% for ZN smear, 77.1%, 97.67%, 97.36%, 79.24% for LJ culture, 89.9%, 67.4%, 75.4%, 85.3% for IGRA, and 66.6%, 95.3%, 94.1%, 71.9% for real-time PCR, respectively. Conclusion: Albeit confounding in the case of latent TB infected patients presenting with non-TB pulmonary disease, IGRA was more sensitive than the other conventional and molecular methods, so it may improve diagnostic accuracy when used in combination with other standard methods. High NPV of IGRA for the diagnosis of active TB proposed an additional role of this test to exclude the infection with active TB.

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New Developments and Perspectives

Cited by 2 publications

References 30 publications

Morphological evaluation of the iliac and femoral arteries; possibilities and perspectives

Morphological evaluation of the iliac and femoral arteries; possibilities and perspectives

Utility of an interferon-gamma release assay as a potential diagnostic aid for active pulmonary tuberculosis

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