New developments in the pathology of malignant lymphoma: a review of the literature published from May to July 2008

New developments in the pathology of malignant lymphoma: a review of the literature published from August to December 2008

“…CD69 expression on tumor cells was a poor prognostic sign, and an interfollicular infiltrate of FoxP3-positive T cells was a good prognostic sign irrespective of the treatment arm, and the authors suggest that a dense infiltrate of FoxP3-positive T cells, dense and interfollicular infiltrate of CD68-positive macrophages, and complete follicular dendritic meshworks were associated with a favorable time to progression in CVP-treated patients, while being a poor prognostic sign in fludarabine-treated patients. This finding confirms the importance of moving away from prognostic marker studies and go to predictive markers (van Krieken [ 4 ]). Ai et al [ 5 ] did in vivo experiments that partially explain the findings of de Jong et al: follicular lymphoma B cells in contrast to normal B cells could induce conventional T cells to express FoxP3 and to acquire regulatory function.…”

New developments in the pathology of malignant lymphoma. A review of the literature published from August 2013 to December 2013

“…CD69 expression on tumor cells was a poor prognostic sign, and an interfollicmacrophages, and complete follicular dendritic meshworks were associated with a favorable time to progression in CVP-treated patients, while being a poor prognostic sign in fludarabine-treated patients. This finding confirms the importance of moving away from prognostic marker studies and go to predictive markers (van Krieken [4]). Ai et al [5] did in vivo experiments that partially explain the findings of de Jong et al: follicular lymphoma B cells in contrast to normal B cells could induce conventional T cells to express FoxP3 and to acquire regulatory function.…”

New developments in the pathology of malignant lymphoma: a review of the literature published from April 2010–July 2010

“…In China, thyroid lymphomas were also studied, like in other countries (see previous review, van Krieken [25]). Sun et al [26] studied 40 cases and show that combined chemotherapy and radiotherapy may offer better outcome without the need for extensive resection, and surgery should be reserved to providing tissue for diagnosis.…”