New Diagnostic Applications in Sporotrichosis

Zancopé‐Oliveira, Rosely Maria; Almeida‐Paes, Rodrigo; Oliveira, Manoel Marques Evangelista; Freitas, Dayvison Francis Saraiva; Galhardo, Maria Clara Gutierrez

doi:10.5772/23590

Cited by 8 publications

(9 citation statements)

References 70 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…cultivated or parasitized at 35-37°C have yellowish-beige colonies with a creamy appearance (Rippon, 1988), where in (Figure 1B) yeast-like colonies are observed on BHI (Brain Heart Infusion) agar after 10 days of incubation at 36°C. Microscopically, they appear as oval, globose or cigar-shaped unicellular yeasts that may have one or more buds (Zancopé-Oliveira et al, 2011), as in (Figure 1D) there is a microscopy of yeast cells stained with lactophenol cotton blue showing cigar-shaped buds at (400X magnification).…”

Section: Etiological Agentementioning

confidence: 93%

“…However, some strains have the ability to form dark colonies from the start of growth (Zancopé-Oliveira et al, 2011).…”

Section: Etiological Agentementioning

confidence: 99%

“…In laboratory diagnosis, the components of Sporothrix spp. are rarely visible on direct examination (Kwon-Chung & Bennett, 1992;Zancopé-Oliveira et al, 2011). Sometimes, in Giemsa-stained smears, a yeast-like cigar or navette shape can be seen with a halo around it.…”

Section: Mycological Aspects Of the Sporothrix Schenckii Complex In F...mentioning

confidence: 99%

See 2 more Smart Citations

Sporothrix schenckii complex in felines: Analysis of clinical, mycological, environmental and epidemiological factors

Rezende

2024

RSD

View full text Add to dashboard Cite

Sporotrichosis is an infectious and chronic fungal disease caused by fungi belonging to the Sporothrix schenckii complex that affects humans and animals through traumatic implantation of the fungus in the skin. They are dimorphic, saprophytic and geophilic fungi that are widely distributed in nature, especially in soils rich in organic matter. The aim of this study was to understand the clinical, mycological, environmental and epidemiological aspects of the Sporothrix schenckii complex in felines. In order to meet the objectives of this research, a qualitative, descriptive and exploratory data survey was carried out through a bibliographic review based on works published in the last 23 years. Sporothrix spp. is considered to be a complex of at least six cryptic species, in other words, they have similar morphological characteristics but different genotypes. In cats, the incubation period is variable; it usually lasts 14 days. On penetrating the tissue, the micellar form transforms into yeast, which generates an inflammatory response and proliferation of the microorganism at the site, causing papular and nodular lesions which, in some cases, heal spontaneously. Therefore, it is clear that sporotrichosis is caused by dimorphic fungi of the Sporothrix schenkii complex. It is a zoonotic disease of great importance in the context of public health, since it is still a neglected disease and requires robust measures to control. As well as being the most seriously affected, felines are the main transmitters to humans and animals, making them a key point in controlling outbreaks of the disease.

show abstract

Section: Etiological Agentementioning

confidence: 93%

“…However, some strains have the ability to form dark colonies from the start of growth (Zancopé-Oliveira et al, 2011).…”

Section: Etiological Agentementioning

confidence: 99%

See 1 more Smart Citation

Sporothrix schenckii complex in felines: Analysis of clinical, mycological, environmental and epidemiological factors

Rezende

2024

RSD

View full text Add to dashboard Cite

show abstract

“…The classic form of sporotrichosis transmission occurs through a cutaneous trauma with wooden splinters or rose bush thorns, for example, and affects mainly farmers, gardeners, or individuals who have contact with these and other organic substrates, which are the habitat of the sporotrichosis agents that grow in their filamentous phase in these substrates [8][9][10][11]. Rare cases of infection through the inhalation of fungal conidia may occur, causing pulmonary sporotrichosis [12].…”

Section: Introduction 1sporotrichosismentioning

confidence: 99%

“…The clinical forms of sporotrichosis are variable and related to the immune status of the host, the burden and depth of the fungal inoculum, and the pathogenicity and thermotolerance of the fungal strain [11,[15][16][17]. There are localized forms, with sole involvement of the skin, corresponding to the most part of the clinical presentations, and disseminated forms, which are less frequent, with skin, pulmonary, bone, meningoencephalic, and mucosal involvement [18,19].…”

Section: Introduction 1sporotrichosismentioning

confidence: 99%

The State of the Art in Transcriptomics and Proteomics of Clinically Relevant Sporothrix Species

Procópio-Azevedo

Almeida

Almeida‐Paes

et al. 2023

JoF

View full text Add to dashboard Cite

Proteomics provide a robust approach to profile and quantify proteins within cells, organs, or tissues, providing comprehensive insights about the dynamics of cellular processes, modifications, and interactions. Similarly, understanding the transcriptome is essential to decipher functional elements of the genome, unraveling the mechanisms of disease development and the molecular constituents of cells and tissues. Some thermodimorphic fungi of the genus Sporothrix cause sporotrichosis, a subcutaneous mycosis of worldwide relevance. The transcriptome and proteome of the main Sporothrix species of clinical interest can elucidate the mechanisms underlying pathogenesis and host interactions. Studies of these techniques can contribute to the advancement of novel diagnostic and therapeutic strategies. A literature review was carried out, addressing all articles based on proteomics using mass spectrometry and transcriptomics of Sporothrix spp. Twenty-one studies were eligible for this review. The main findings include proteins and genes involved in dimorphism, cell differentiation, thermotolerance, virulence, immune evasion, metabolism, cell adhesion, cell transport, and biosynthesis. With the spread and emergence of sporotrichosis in different countries, ongoing research efforts and new discoveries are welcome to advance knowledge about this mycosis and its agents.

show abstract

Clinical, Epidemiological, and Epizootic Features of Sporothrix brasiliensis in Espírito Santo, Brazil

et al. 2022

View full text Add to dashboard Cite

New Diagnostic Applications in Sporotrichosis

Cited by 8 publications

References 70 publications

Sporothrix schenckii complex in felines: Analysis of clinical, mycological, environmental and epidemiological factors

Sporothrix schenckii complex in felines: Analysis of clinical, mycological, environmental and epidemiological factors

The State of the Art in Transcriptomics and Proteomics of Clinically Relevant Sporothrix Species

Clinical, Epidemiological, and Epizootic Features of Sporothrix brasiliensis in Espírito Santo, Brazil

Contact Info

Product

Resources

About