New Discoveries in Medicine and Physiology Originated in Urology

Ghanem, Ahmed N

doi:10.31031/smoaj.2020.03.000564

SMOAJ

2020

DOI: 10.31031/smoaj.2020.03.000564

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New Discoveries in Medicine and Physiology Originated in Urology

Ahmed N Ghanem¹

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2020

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“…This was accompanied by critical analytical literature review of all the related issues. These have resulted in many new discoveries in physics, medicine and physiology [29]. The analytical literature review is reported here.…”

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confidence: 99%

Volumetric Overload Shocks Cause the Acute Respiratory Distress Syndrome: Building the Bridge Between Physics, Physiology, Biochemistry, and Medicine

Ghanem

2020

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The acute respiratory distress syndrome (ARDS) was first reported in 19671. Volumetric overload (VO) of 12-14 liters (L) reported in every case but not incriminated in patho-aetiology. Although fluid therapy has been suspected [1-8] and prospective trials reported VO of 3-10 L in surviving ARDS patients7,8, it has not been incriminated [2-8]. ARDS is attributed to sepsis [9-12], has a high morbidity, cost and mortality [2-12]. How the precise role of VO in patho-aetiology of ARDS was unraveled and the BRIDGE between physics, physiology, biochemistry, and medicine was built, remain unknown. Here I show how VO complicates fluid therapy during shock resuscitation inducing the new shock (VOS) [13-20] unraveled by critical analytical review of key articles as well as my own research, while building the BRIDGE between basic sciences and medicine. The new VOS is of two types: VOS 1 and VOS 2.Hyponatraemia characterizes VOS 1 that is mistaken for a recognized shock and wrongly treated with further volume expansion complicating into VOS 2 causing secondary ARDS17-20.

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confidence: 99%

Volumetric Overload Shocks Cause the Acute Respiratory Distress Syndrome: Building the Bridge Between Physics, Physiology, Biochemistry, and Medicine

Ghanem

2020

BJSTR

Self Cite

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New Discoveries in Medicine and Physiology Originated in Urology

Cited by 1 publication

References 13 publications

Volumetric Overload Shocks Cause the Acute Respiratory Distress Syndrome: Building the Bridge Between Physics, Physiology, Biochemistry, and Medicine

Volumetric Overload Shocks Cause the Acute Respiratory Distress Syndrome: Building the Bridge Between Physics, Physiology, Biochemistry, and Medicine

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