New Drugs for Bipolar Disorder

Sanches, Marsal; Soares, Jair C.

doi:10.1007/s11920-011-0231-1

Cited by 5 publications

(4 citation statements)

References 68 publications

(55 reference statements)

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“…Preclinical and clinical evidence suggests that this agent may have a beneficial role in the treatment of acute mania. 69 In addition, anecdotal reports indicate that it may also have positive effects on the cognition of bipolar patients. 70,71 It is yet unclear whether the cognition-enhancing properties of memantine are independent of its effects on mood symptomatology.…”

Section: Therapeutic Approach For Cognitive Impairment In Bdmentioning

confidence: 99%

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The Management of Cognitive Impairment in Bipolar Disorder

Sanches

Bauer

Gálvez

et al. 2015

American Journal of Therapeutics

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Bipolar disorder (BD) is associated with important cognitive deficits that persist during the periods of remission. Although these deficits seem to play an important role in the functional impairment experienced by bipolar patients, evidence regarding their clinical management is scant. We revised the databases PubMed, MEDLINE, and clinicaltrials.gov, searching for studies focusing on the pharmacological and nonpharmacological treatment of cognitive deficits among bipolar patients. In addition, a manual search of bibliographical cross-references was performed. Currently, there is no Food and Drug Administration–approved pharmacological agent for the management of cognitive deficits in BD. A number of agents have been tested in the treatment of cognitive deficits in BD, with mixed results. Nonpharmacological interventions, such as cognitive remediation and noninvasive brain stimulation techniques, seem promising, but their role has not yet been properly explored among bipolar patients. Additional studies, aiming at evaluating the efficacy of interventions combining cognitive rehabilitation and biological treatments, are highly desirable.

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Section: Therapeutic Approach For Cognitive Impairment In Bdmentioning

confidence: 99%

“…69 An ongoing clinical trial is currently assessing its impact on the cognitive performance of stable bipolar patients. 7 …”

Section: Therapeutic Approach For Cognitive Impairment In Bdmentioning

confidence: 99%

The Management of Cognitive Impairment in Bipolar Disorder

Sanches

Bauer

Gálvez

et al. 2015

American Journal of Therapeutics

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“…Bipolar disorder (BD) and borderline personality disorder (BPD) are among the most prevalent and frequently diagnosed psychiatric conditions. Both are associated with increased morbidity, elevated rates of suicide, and considerable functional impairment [1,2,3]. While the concept of BD has, over the past several years, been fully incorporated by culture [4], most of the general public is not yet completely familiar with the diagnosis of BPD, despite its popularity among psychiatrists and mental health providers.…”

Section: Introductionmentioning

confidence: 99%

The Limits between Bipolar Disorder and Borderline Personality Disorder: A Review of the Evidence

Sanches

2019

Diseases

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Bipolar disorder and borderline personality disorder are among the most frequently diagnosed psychiatric conditions. However, the nosological aspects and diagnostic boundaries of both conditions have historically been the object of considerable controversy. The present paper critically analyzes this debate, in light of available evidence. Clinical and neurobiological differences between bipolar disorder and borderline personality disorder are discussed, as well as the factors possibly involved in the overlap between both conditions and the potential implications of this.

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“…For example, in patients with manic performance, irritability often stems from impatience, which is often secondary to exaggerated ideas, increased energy, accelerated thought processes, etc. ; however, in patients with other disorders, irritability may be for other reasons [19].…”

Section: The Confusion Between Agitated Depression Disruptive Mood Dy...mentioning

confidence: 99%

Research on the Over Diagnosis of Bipolar Disorder among Teenagers in China

Liu

2023

LNEP

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Recent research has revealed that the diagnosis rate of bipolar disorder is increasing rapidly, especially among adolescents. Although some attempts have been made to address this issue, it is still worth further research. This paper provides new insights into the phenomenon that bipolar disorder has been overdiagnosed among teenagers in China. Basically, the purpose of this paper is to make a more comprehensive and in-depth analysis of the background, current situation, controversy, factors, and possible consequences of the overdiagnosis of bipolar disorder. In the following, this paper introduces some domestic and foreign research results, and shares authoritative opinions and reflections about the overdiagnosis of bipolar disorder. To conclude, this paper provides detailed information about the overdiagnosis of bipolar disorder, analyzes the status quo of psychiatric diagnosis and summarizes related literature, suggesting that the process of diagnosing bipolar disorder is problematic. Therefore, its essential for us to revisit our diagnostic criteria as well as proper treatment.

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New Drugs for Bipolar Disorder

Cited by 5 publications

References 68 publications

The Management of Cognitive Impairment in Bipolar Disorder

The Management of Cognitive Impairment in Bipolar Disorder

The Limits between Bipolar Disorder and Borderline Personality Disorder: A Review of the Evidence

Research on the Over Diagnosis of Bipolar Disorder among Teenagers in China

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