New endoscopic ultrasonography criteria for malignant lymphadenopathy based on inter-rater agreement

Takasaki, Yusuke; Irisawa, Atsushi; Shibukawa, Goro; Sato, Ai; Abe, Yoko; Yamabe, Akane; Arakawa, Noriyuki; Maki, Takumi; Yoshida, Yuichiro; Igarashi, Ryo; Yamamoto, Shozo; Ikeda, Tsunehiko

doi:10.1371/journal.pone.0212427

Cited by 9 publications

(8 citation statements)

References 21 publications

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“…Takasaki et al evaluated the IOR of EUS features and proposed EUS diagnostic norms for lymphadenopathy based on the IOR [ 58 ]. The IOR was moderate for shape ( K = 0.44) and fair for echogenicity, homogeneity, border, and hilum of the lymph node ( K = 0.33, 0.34, 0.22, and 0.22, respectively).…”

Section: Other Diseasesmentioning

confidence: 99%

Interobserver Reliability of Endoscopic Ultrasonography: Literature Review

et al. 2020

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Endoscopic ultrasonography (EUS) has been applied to the diagnosis of various digestive disorders. Although it has been widely accepted and its diagnostic value is high, the dependence of EUS diagnosis on image interpretation done by the endosonographer has persisted as an important difficulty. Consequently, high interobserver reliability (IOR) in EUS diagnosis is important to demonstrate the reliability of EUS diagnosis. We reviewed the literature on the IOR of EUS diagnosis for various diseases such as chronic pancreatitis, pancreatic solid/cystic mass, lymphadenopathy, and gastrointestinal and subepithelial lesions. The IOR of EUS diagnosis differs depending on the disease; moreover, EUS findings with high IOR and those with IOR that was not necessarily high were used as diagnostic criteria. Therefore, to further increase the value of EUS diagnosis, EUS diagnostic criteria with high diagnostic characteristics based on EUS findings with high IOR must be established.

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Section: Other Diseasesmentioning

confidence: 99%

Interobserver Reliability of Endoscopic Ultrasonography: Literature Review

et al. 2020

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“…Endosonographic characteristics of malignant lymph nodes include large size, hypoechogenicity, distinct border, round shape, and high tissue stiffness on elastography [ 5 , 6 ]. Nevertheless, the lymph node appearance on EUS alone is not sufficient to firmly distinguish benign nodes from malignant ones [ 7 ]. Instead, pathology is required to confirm the underlying etiology.…”

Section: Introductionmentioning

confidence: 99%

“…less, the lymph node appearance on EUS alone is not sufficient to firmly distinguish benign nodes from malignant ones. 7 Instead, pathology is required to confirm the underlying etiology.…”

mentioning

confidence: 99%

High Sensitivity of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Endoscopic Ultrasound-Guided Fine-Needle Biopsy in Lymphadenopathy Caused by Metastatic Disease: A Prospective Comparative Study

et al. 2021

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Diagnosing unclear lymphadenopathy such as lymph node metastasis has an enormous impact on the treatment of neoplastic diseases. Therefore, the aim of treatment usually switches from cure to palliation. Numerous other diseases are accompanied by lymphadenopathy, including benign conditions such as infections and inflammatory disease. 1 Hence, sampling of the target node is often required to unveil the underlying diagnosis and to enable adequate clinical management. 2 Intrathoracic or intraabdominal lymphadenopathies are clinically challenging because the nodes are difficult to sample using non-invasive techniques. Therefore, invasive methods such as mediastinoscopy or laparotomy are needed but are associated with risks. 3 A mini-invasive method such as endosonography (EUS) is an alternative approach in such scenarios. 4 Endosonographic characteristics of malignant lymph nodes include large size, hypoechogenicity, distinct border, round shape, and high tissue stiffness on elastography. 5,6 Neverthe

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“…All US images were interpreted through consensus, with blinding of patient information and pathological diagnosis. US ndings, such as isoechoic/hypoechoic levels, homogeneous texture, absence of hilar echoes, expansion appearance, and peripheral/mixed vascularity, were selected as characteristics of suspected malignancy, as per earlier reports [13,15,[28][29][30][31][32][33].…”

Section: Us Protocol and Evaluationmentioning

confidence: 99%

Transabdominal ultrasonography for the preoperative diagnosis of advanced lymph node metastasis in patients with colon cancer: A retrospective cohort study

Imaizumi

Homma

Nishida

et al. 2021

Preprint

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Purpose Although computed tomography (CT) has been the standard modality for diagnosing lymph node metastasis (LNM), transabdominal ultrasonography (US) can be useful due to its high spatial resolution and use of Doppler signals to precisely analyze lymph nodes. This study aimed to evaluate the accuracy of US for lymph node assessment, establish US-based diagnostic criteria for LNM, and compare the capability of US with CT for the diagnosis of LNM. Methods This retrospective, single-institution, cohort study included patients who underwent radical surgery for clinical stage 0–III colon cancer, between March 2012 and February 2019. Results Overall, 34.9% (66/189) of patients had pathological LNM. The optimal US diagnostic criteria were (1) short axis ≥ 7 mm and short/long ratio ≥ 0.75 and (2) at least two of the following: the absence of hilar echoes, expansive appearance, or peripheral/mixed vascularity vascularity by the color Doppler and/or contrast-enhanced method. US showed a higher diagnostic sensitivity (54.5% vs. 43.9%; P = 0.296), higher concordance with the number of pathological LNM (correlation coefficient: US, 0.42; CT, 0.27) and pathological N diagnosis (weighted κ: US, 0.35; CT, 0.18), and higher sensitivity for advanced LNM, including multiple LNMs (47.4% vs 18.4%; P = 0.014) and N2 stage (27.8% vs 5.6%; P = 0.177), than CT. Conclusions US has higher sensitivity than CT for diagnosing LNM in colon cancer, along with a more accurate preoperative diagnosis of the N stage. Thus, US may be more helpful than CT for preoperatively deciding the appropriateness of neoadjuvant treatment in patients with colon cancer with advanced LNM.

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New endoscopic ultrasonography criteria for malignant lymphadenopathy based on inter-rater agreement

Cited by 9 publications

References 21 publications

Interobserver Reliability of Endoscopic Ultrasonography: Literature Review

Interobserver Reliability of Endoscopic Ultrasonography: Literature Review

High Sensitivity of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Endoscopic Ultrasound-Guided Fine-Needle Biopsy in Lymphadenopathy Caused by Metastatic Disease: A Prospective Comparative Study

Transabdominal ultrasonography for the preoperative diagnosis of advanced lymph node metastasis in patients with colon cancer: A retrospective cohort study

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