New evidence in trauma resuscitation - is 1:1:1 the answer?

Miller, Timothy E.

doi:10.1186/2047-0525-2-13

Cited by 50 publications

(46 citation statements)

References 46 publications

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“…Contrary to traditional teaching, resuscitation with large volumes of crystalloid in trauma patients has now been replaced by targeted blood and blood product transfusion. 22,23 In terms of rapid fluid resuscitation, in one retrospective study, those patients surviving from traumatic cardiac arrest had significantly more fluid resuscitation than those non-survivors (although blood products were not used in this study). 24 The role of thoracotomy.…”

Section: Management Of Reversible Causesmentioning

confidence: 99%

Traumatic cardiac arrest

2015

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Traumatic cardiac arrest is known to have a poor outcome, and some authors have stated that attempted resuscitation from traumatic cardiac arrest is futile. However, advances in damage control resuscitation and understanding of the differences in pathophysiology of traumatic cardiac arrest compared to medical cardiac arrest have led to unexpected survivors. Recently published data have suggested that outcome from traumatic cardiac arrest is no worse than that for medical causes of cardiac arrest, and in some groups may be better. This review highlights key areas of difference between traumatic cardiac arrest and medical cardiac arrest, and outlines a strategy for the management of patients in traumatic cardiac arrest. Standard Advanced Life Support algorithms should not be used for patients in traumatic cardiac arrest.

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Section: Management Of Reversible Causesmentioning

confidence: 99%

Traumatic cardiac arrest

2015

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“…These complexities may explain the failure of systematic reviews to find consistent clinical benefits of plasma transfusion, except in plasma exchange for thrombotic thrombocytopenic purpura . Plasma transfusion remains a commonly prescribed procedure and many clinicians remain convinced of its value; indeed its earlier and more aggressive use has been advocated in trauma settings …”

mentioning

confidence: 99%

The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice

Eltringham-Smith

Adili

et al. 2014

Transfusion

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“…Treatment must involve external compression to stop further loss, gaining access to wide-bore cannula, and initiate rapid transfusion of blood and blood products along with the attempts of CPR. In contrast to the traditional teaching, blood and blood products are preferred over the crystalloid transfusion [97,98]. Although supportive evidence has demonstrated improved survival in patients receiving more fluid resuscitation (crystalloids) [99].…”

Section: Hypovolemia and Rapid Fluid Resuscitationmentioning

confidence: 99%

Cardiopulmonary Resuscitation: Recent Advances

Kumar¹,

Yadav²,

Garg³

2020

Sudden Cardiac Death

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Cardiac arrest is the most significant reason for mortality and morbidities worldwide. With a better understanding of the pathophysiology of cardiac arrest, simple adaptations in basic life support to upcoming modifications in postresuscitation care have been proposed by various resuscitation councils throughout the globe. Role of point of care cardiac ultrasound during cardiopulmonary resuscitation (CPR) has been explored and its contribution for identifying reversible causes and its real time management has been explored. A higher blood and tissue oxygenation levels contributed to an increased rate of return of spontaneous circulation (ROSC) which has to lead us to explore more options to increase the oxygenation. Starting from the CPR training, the use of sensors for spirometric feedback in ventilation maneuvers can help improve the quality of CPR. High flow nasal oxygenation during CPR has shown promising results. Extracorporeal CPR is another entity that has shown survival benefits in a selected group of patients. The aim of the newer advances has always been to decrease the morbidity and improve survival outcomes in terms of neurological deficit as well. These guidelines are reviewed and updated regularly to improve knowledge and training based on the current evidence. This chapter shall focus on recent advances in cardiopulmonary resuscitation.

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New evidence in trauma resuscitation - is 1:1:1 the answer?

Cited by 50 publications

References 46 publications

Traumatic cardiac arrest

Traumatic cardiac arrest

The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice

Cardiopulmonary Resuscitation: Recent Advances

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