<abstract><p>This paper study was designed to establish solutions for mixed functional fractional integral equations that involve the Riemann-Liouville fractional operator and the Erdélyi-Kober fractional operator to describe biological population dynamics in Banach space. The results rely on the measure of non-compactness and theoretical concepts from fractional calculus. Darbo's fixed-point theorem for Banach spaces has been utilized. Moreover, the solvability of a specific non-linear integral equation that models the spread of infectious diseases with a seasonally varying periodic contraction rate has been explored by using the Banach contraction principle. Finally, two numerical examples demonstrate the practical application of these findings in the realm of fractional integral equation theory.</p></abstract>