New Fluorescent Rhodamine Hydrazone Chemosensor for Cu(II) with High Selectivity and Sensitivity

Abstract

[reaction: see text] A new fluorescent probe, salicylaldehyde rhodamine B hydrazone (1), was synthesized and displayed selective Cu(II)-amplified absorbance and fluorescence emission above 500 nm in neutral buffered media. Upon the addition of Cu(II), the spirolactam ring of 1 was opened and a 1:1 metal-ligand complex was formed. The detection of Cu(II) by 1 at a lower micromolar level was successful even in buffered water.

A sensitive fluorescent biosensor for the detection of copper ion inspired by biological recognition element pyoverdine

“…As shown in Fig. 4a and b, a good linear correlation was obtained between the quenching efficiency and the concentration of copper ion from 0.2 to 10 M. And the detection limit of biosensor pyoverdine to copper ion was up to 50 nM (signal to noise ratio equal to 3.0), which was equal with the established copper ion fluorescence probes by polyamine-functionalized carbon quantum dots and pyoverdine-similar chemosensors [14,36,37]. The results indicated that the developed biosensor can detect copper ion with satisfied sensitivity.…”

Rhodamine Based Fluorescent Chemosensors for Hg2+and its Biological Application

“…8 Xiang et al used a rhodamine-based hydrazine bearing a salicyaldehyde binding site as a Cu 2+ amplified sensor. 9 Tae group reported a Hg 2+ chemosensor based on the rhodamine-hydrazine framework.…”

Colorimetric Detection of Copper (II) Based on the Self-Assembly of Schiff’s Base-Functionalized Gold Nanoparticles

“…Up to now, several methods for Cu 2+ detection have been reported, including organic fluorophore-based assays (Viguier et al, 2006;Xiang et al, 2006), atomic absorption spectroscopy (AAS) (Gonzales et al, 2009), inductively coupled plasma mass spectroscopy (ICP-MS) (Becker et al, 2005), ICP-AES (atomic emission spectroscopy) (Liu et al, 2005) and some electrochemical assays (Ensafi et al, 2006;Karimi et al, 2006). Although the sensitivities of these developed methods for Cu 2+ are generally high, most of these assays need either expensive and speciallized instruments or sophisticated assay procedures, which greatly limited their wide applications.…”