Vital plant functions require at least six metals (copper, iron, molybdenum, manganese, zinc, nickel) which function as enzyme cofactors or inducers. In the past decades, the rapidly evolving nanotechnology has created nanoforms of essential metals (e.g. nZnO, nFe2O3 etc.), having a number of favourable properties over the bulk material. The effects of nanometals on plants are concentration-dependent (hormesis), but also depend on the properties of the nanometals, the plants species and the treatment conditions. This review collects studies examining plant responses to essential nanometal treatments using (multi)omics approach and emphasizes the importance of gaining a holistic view of the diversified effects. Furthermore, the review discusses the beneficial effects of essential nanometals on plants, which provides the basis for their applicability in crop production as nanopriming or nanostimulator agents, nanofertilizers etc. As by the application of essential nanometals lower environmental impact and increased yield can be achieved, nanometals support sustainable agriculture. Recent studies actively examine the utilization of green-synthetized metal nanoparticles, which perfectly fits into the environmental-friendly trend of future agriculture.
There is still a long way to go before essential nanometals can be safely applied in agricultural, but it is certainly a promising direction that is timely to investigate.