New frontiers in water purification: highly stable amphopolycarboxyglycinate-stabilized Ag–AgCl nanocomposite and its newly discovered potential

Krutyakov, Yu. A.; Zherebin, Pavel M; Kudrinskiy, A. A.; Zubavichus, Yan V.; Presniakov, M. Yu.; Yapryntsev, A. D.; Karabtseva, Anastasia V; Mikhaylov, Dmitry M.; Лисичкин, Г. В.

doi:10.1088/0022-3727/49/37/375501

Cited by 12 publications

(3 citation statements)

References 52 publications

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“…Synthesized Ag/AgCl composite particles containing metallic silver and silver halogenide are reported to have a core-shell structure with an Ag shell on the surface of silver halogenide NPs (Dong, Liang, and Gong 2012;Krutyakov et al 2016b).…”

Section: Resultsmentioning

confidence: 99%

“…Colloidal solutions of AgNPs were obtained using a procedure published elsewhere (Krutyakov et al 2016a;Krutyakov et al 2016b;Gusev et al 2016). Briefly, 50 mL of an aqueous solution of AgNO 3 (0.395 g, 0.185 mmol) was added dropwise to a 50 mL aqueous solution of a stabilizer under vigorous stirring.…”

Section: Synthesis Of 200 ML Colloids Of Ag Nps With a Concentration mentioning

confidence: 99%

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The effect of capping agents on the toxicity of silver nanoparticles to Danio rerio embryos

et al. 2019

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Addition of capping agents like surfactants and polymers during the synthesis of nanoparticles may affect the stability and toxicity of dispersions of nanoparticles. This study revealed the impact of anionic, cationic, and amphoteric surfactants and a cationic polymer on the physical and chemical properties, stability and behavior of silver nanomaterials, as well as on the toxicity of nanosized silver particles with respect to zebrafish embryos. Some of the stabilizers applied were shown to significantly affect embryos of Danio rerio. Colloidal dispersions of stabilized silver nanoparticles were demonstrated to induce a complex mechanism of toxicity with respect to embryos of D. rerio, which is mainly explained by the toxicity of the organic ligand, while other parameters are somewhat inferior. The newly generated data on the toxicity of nanoparticles and their stabilizers with respect to D. rerio embryos reveal the complexity of the toxicity mechanism of nanoparticles impacting living systems. ARTICLE HISTORY

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Section: Resultsmentioning

confidence: 99%

Section: Synthesis Of 200 ML Colloids Of Ag Nps With a Concentration mentioning

confidence: 99%

The effect of capping agents on the toxicity of silver nanoparticles to Danio rerio embryos

et al. 2019

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“…BAC is a well-known active ingredient used in many antiseptic medicines. It was assumed that modification of the AgNPs surface with a cationic surfactant displaying no toxicity against mammal cells [ 40 , 41 ], and possessing antibacterial properties [ 42 , 43 , 44 , 45 ] would produce a highly effective antibacterial agent containing small-diameter AgNPs with the positive surface charge that would require no additional surface modification or purification [ 46 , 47 , 48 , 49 ]. During in vitro experiments we confirmed high effectiveness of AgNPs-BAC.…”

Section: Introductionmentioning

confidence: 99%

In Vivo Study of Entero- and Hepatotoxicity of Silver Nanoparticles Stabilized with Benzyldimethyl-[3-myristoylamine)-propyl]ammonium Chloride (Miramistin) to CBF1 Mice upon Enteral Administration

et al. 2021

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Silver nanoparticles (AgNPs) are the most widely studied antimicrobial nanomaterials. However, their use in biomedicine is currently limited due to the availability of data that prove the nanosilver toxicity associated primarily with oxidative stress development in mammalian cells. The surface modification of AgNPs is a potent technique of improvement of their biocompatibility. The synthetic or natural compounds that combine zero or low toxicity towards human and animal organisms with inherent antimicrobial properties are the most promising stabilizing agents, their use would also minimize the risks of microorganisms developing resistance to silver-based materials. We used a simple technique to obtain 30–60 nm AgNPs stabilized with benzyldimethyl[3-myristoylamine)-propyl]ammonium chloride monohydrate (BAC)—a well-known active ingredient of many antibacterial drugs. The objective of the study was to assess the AgNPs-BAC entero- and hepatotoxicity to CBF1 mice upon enteral administration. The animals were exposed to 0.8–7.5 mg/kg doses of AgNPs-BAC in the acute and to 0.05–2.25 mg/kg doses of AgNPs-BAC in the subacute experiments. No significant entero- and hepatotoxic effects following a single exposure to doses smaller than 4 mg/kg were detected. Repeated exposure to the doses of AgNPs-BAC below 0.45 mg/kg and to the doses of BAC below 0.5 mg/kg upon enteral administration also led to no adverse effects. During the acute experiment, the higher AgNPs-BAC dose resulted in increased quantities of aminotransferases and urea, as well as the albumin-globulin ratio shift, which are indicative of inflammatory processes. Besides, the relative mass of the liver of mice was smaller compared to the control. During the subacute experiment, the groups treated with the 0.25–2.25 mg/kg dose of AgNPs-BAC had a lower weight gain rate compared to the control, while the groups treated with the 2.25 mg/kg dose of AgNPs-BAC showed statistically significant variations in the blood serum transaminases activity, which indicated hepatosis. It should be noted that the spleen and liver of the animals from the groups treated with the 0.45 and 2.25 mg/kg dose of AgNPs-BAC were more than two times smaller compared to the control. In the intestines of some animals from the group treated with the 2.25 mg/kg dose of AgNPs-BAC small areas of hyperemia and enlarged Peyer’s patches were observed. Histological examination confirmed the initial stages of the liver and intestinal wall inflammation.

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Correlation between the rate of silver nanoparticle oxidation and their biological activity: the role of the capping agent

et al. 2019

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New frontiers in water purification: highly stable amphopolycarboxyglycinate-stabilized Ag–AgCl nanocomposite and its newly discovered potential

Cited by 12 publications

References 52 publications

The effect of capping agents on the toxicity of silver nanoparticles to Danio rerio embryos

The effect of capping agents on the toxicity of silver nanoparticles to Danio rerio embryos

In Vivo Study of Entero- and Hepatotoxicity of Silver Nanoparticles Stabilized with Benzyldimethyl-[3-myristoylamine)-propyl]ammonium Chloride (Miramistin) to CBF1 Mice upon Enteral Administration

Correlation between the rate of silver nanoparticle oxidation and their biological activity: the role of the capping agent

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